Author name: Kristen Hartman

Reduced microglial activity and enhanced glutamate transmission in the basolateral amygdala in early CNS autoimmunity

Acharjee S, Verbeek M, Gomez CD, Bisht K, Lee B, Benoit L, Sharkey KA, Benediktsson A, Tremblay M-E, Pittman QJ (2018) Reduced microglial activity and enhanced glutamate transmission in the basolateral amygdala in early CNS autoimmunity. J Neurosci 38:9019-9033. doi: 10.1523/JNEUROSCI.0398-18.2018 Objective: To identify CNS changes associated with behaviors in multiple sclerosis (MS) patients. Summary: […]

Reduced microglial activity and enhanced glutamate transmission in the basolateral amygdala in early CNS autoimmunity Read More »

Hypoglossal motor neuron death via intralingual CTB-saporin (CTB-SAP) injections mimic aspects of amyotrophic lateral sclerosis (ALS) related to dysphagia

Lind LA, Murphy ER, Lever TE, Nichols NL (2018) Hypoglossal motor neuron death via intralingual CTB-saporin (CTB-SAP) injections mimic aspects of amyotrophic lateral sclerosis (ALS) related to dysphagia. Neuroscience 390:303-316. doi: 10.1016/j.neuroscience.2018.08.026 Objective: Despite its fundamental importance, dysphagia (difficulty swallowing) and strategies to preserve swallowing function have seldom been studied in ALS models. Summary: The

Hypoglossal motor neuron death via intralingual CTB-saporin (CTB-SAP) injections mimic aspects of amyotrophic lateral sclerosis (ALS) related to dysphagia Read More »

Comparison of two different media for maturation rate of neural progenitor cells to neuronal and glial cells emphasizing on expression of neurotrophins and their respective receptors

Ebadi R, Kordi-Tamandani DM, Ghaedi K, Nasr-Esfahani MH (2018) Comparison of two different media for maturation rate of neural progenitor cells to neuronal and glial cells emphasizing on expression of neurotrophins and their respective receptors. 45(6):2377-2391. doi: 10.1007/s11033-018-4404-4 PMID: 30306506 Objective: To compare neural differentiation potential of two different media, NB + 5%ES-FBS + N2B27

Comparison of two different media for maturation rate of neural progenitor cells to neuronal and glial cells emphasizing on expression of neurotrophins and their respective receptors Read More »

Nanoparticle-mediated delivery of Tanshinone IIA reduces adverse cardiac remodeling following myocardial infarctions in a mice model: Role of NF-κB pathway

Mao S, Wang L, Chen P, Lan Y, Guo R, Zhang M (2018) Nanoparticle-mediated delivery of Tanshinone IIA reduces adverse cardiac remodeling following myocardial infarctions in a mice model: Role of NF-κB pathway. Artif Cells Nanomed Biotechnol 46(sup3):S707-S716. doi: 10.1080/21691401.2018.1508028 PMID: 30284484 Objective: To develop a nanoparticle-mediated drug delivery system for Tanshinone IIA. Summary: Demonstrated

Nanoparticle-mediated delivery of Tanshinone IIA reduces adverse cardiac remodeling following myocardial infarctions in a mice model: Role of NF-κB pathway Read More »

Synaptic circuits for irradiance coding by intrinsically photosensitive retinal ganglion cells

Sabbah S, Papendorp C, Koplas E, Beltoja M, Etebari C, Gunesch AN, Carrete L, Kim MT, Manoff G, Bhatia-Lin A, Zhao T, Schreck D, Dowling H, Briggman KL, Berson DM (2018) Synaptic circuits for irradiance coding by intrinsically photosensitive retinal ganglion cells. bioRxiv 442954. doi: 10.1101/442954 Objective: To explore the synaptic networks responsible for the

Synaptic circuits for irradiance coding by intrinsically photosensitive retinal ganglion cells Read More »

Myocyte enhancer factor 2c regulates dendritic complexity and connectivity of cerebellar Purkinje cells.

Kamath SP, Chen AI (2018) Myocyte enhancer factor 2c regulates dendritic complexity and connectivity of cerebellar Purkinje cells. Mol Neurobiol 56:4102–4119. doi: 10.1007/s12035-018-1363-7 PMID: 30276662 Objective: To investigate the roles of Mef2c in cerebellar Purkinje cells during the first three weeks of postnatal development. Summary: Mef2c haploinsufficiency is implicated in behavioral deficits related to autism,

Myocyte enhancer factor 2c regulates dendritic complexity and connectivity of cerebellar Purkinje cells. Read More »

Cell-specific transcriptome analysis shows that adult pillar and deiters’ cells express genes encoding machinery for specializations of cochlear hair cells

Liu H, Chen L, Giffen KP, Stringham ST, Li Y, Judge PD, Beisel KW, He DZZ (2018) Cell-specific transcriptome analysis shows that adult pillar and deiters’ cells express genes encoding machinery for specializations of cochlear hair cells. Front Mol Neurosci 11:356. doi: 10.3389/fnmol.2018.00356 PMID: 30327589 Related Products: NGFr (mu p75) Rabbit Polyclonal, affinity-purified (Cat. #AB-N01AP)

Cell-specific transcriptome analysis shows that adult pillar and deiters’ cells express genes encoding machinery for specializations of cochlear hair cells Read More »

Lacrimal gland denervation alters tear protein composition and impairs ipsilateral eye closures and corneal nociception

Hegarty DM, David LL, Aicher SA (2018) Lacrimal gland denervation alters tear protein composition and impairs ipsilateral eye closures and corneal nociception. Invest Ophthalmol Vis Sci 59:5217-5224. doi: 10.1167/iovs.18-25267 Objective: To evaluate spontaneous and evoked ocular sensory responses in rats after denervation of the lacrimal gland, as well as protein changes in tears that may

Lacrimal gland denervation alters tear protein composition and impairs ipsilateral eye closures and corneal nociception Read More »

Nicotinamide mononucleotide adenylyltransferase 2 maintains neuronal structural integrity through the maintenance of golgi structure.

Pottorf T, Mann A, Fross S, Mansel C, Vohra BPS (2018) Nicotinamide mononucleotide adenylyltransferase 2 maintains neuronal structural integrity through the maintenance of golgi structure. Neurochem Int 121:86-97. doi: 10.1016/j.neuint.2018.09.010 PMID: 30278188 Objective: To Investigate the link between NMNAT2 loss, Golgi fragmentation and axon degeneration Summary: Results degeneration signals converge on a common cytNmnat1 mediated

Nicotinamide mononucleotide adenylyltransferase 2 maintains neuronal structural integrity through the maintenance of golgi structure. Read More »

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