Hegarty DM, David LL, Aicher SA (2018) Lacrimal gland denervation alters tear protein composition and impairs ipsilateral eye closures and corneal nociception. Invest Ophthalmol Vis Sci 59:5217-5224. doi: 10.1167/iovs.18-25267
Objective: To evaluate spontaneous and evoked ocular sensory responses in rats after denervation of the lacrimal gland, as well as protein changes in tears that may mediate functional changes.
Summary: Denervation of the lacrimal gland causes long-lasting hypoalgesia, impairs the blink response, and alters tear proteins.
Usage: 192-IgG-SAP (5 μL, 0.5 μg/μL) was microinjected into the left extraorbital lacrimal gland. In a separate group, 192-IgG-SAP was applied directly and unilaterally to the corneal surface.
Related Products: 192-IgG-SAP (Cat. #IT-01)