Cassandras M, Wang C, Kathiriya J, Tsukui T, Matatia P, Matthay M, Wolters P, Molofsky A, Sheppard D, Chapman H, Peng T (2020) Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nat Cell Biol 22(11):1295-1306. doi: 10.1038/s41556-020-00591-9 PMID: 33046884 Objective: To show that Gli1+ mesenchymal stromal […]
Cops J, De Moor B, Haesen S, Lijnen L, Wens I, Lemoine L, Reynders C, Penders J, Lambrichts I, Mullens W, Hansen D (2020) Endurance exercise intervention is beneficial to kidney function in a rat model of isolated abdominal venous congestion: A pilot study. J Cardiovasc Transl Res 13(5):769-782. doi: 10.1007/s12265-019-09947-5 PMID: 31848881 Objective: To
London M, Gallo E (2020) The EphA2 and cancer connection: potential for immune-based interventions. Mol Biol Rep 47(10):8037-8048. doi: 10.1007/s11033-020-05767-y Summary: The authors review the most current mAb-based therapies against EphA2-expressing cancers currently in pre-clinical and/or clinical stages. They reference Sakamoto et al. who performed in vitro testing of two different EphA2 mAbs mixed with
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Persaud SP, Ritchey JK, Choi J, Ruminski PG, Cooper ML, Rettig MP, DiPersio JF (2020) Antibody-drug conjugates targeting CD45 plus Janus kinase inhibitors effectively condition for allogeneic hematopoietic stem cell transplantation. bioRxiv 2020.10.02.324475. doi: 10.1101/2020.10.02.324475 Related Products: Streptavidin-ZAP (Cat. #IT-27), Blank-Streptavidin-SAP (Cat. #IT-27B)
Guo J, Ba X, Matsuda M, Wei P, Jiang C, Sun W, Xiao L, Xiong D, Liao X, Hao Y (2020) Oxytocin elicits itch scratching behavior via spinal GRP/GRPR system. Front Neursci 14:581977. doi: 10.3389/fnins.2020.581977 PMID: 33071749 Objective: To investigate the spinal mechanisms underlying oxytocin-induced scratching behavior and its relationship with the gastrin-releasing peptide (GRP)/GRP
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Dobryakova YV, Stepanichev MY, Markevich VA, Bolshakov AP (2020) Long-term potentiation in the hippocampal CA3 to CA1 synapses may be induced in vivo by activation of septal cholinergic inputs. Int J Neurosci 23:1-7. doi: 10.1080/00207454.2020.1822834 Objective: To clarify the role of septal input in the development of long-term potentiation (LTP) in this synapse. Summary: Elimination
Li W, Luo S, Wan C (2020) Characterization of fever and sickness behavior regulated by cytokines during infection. Behaviour 157:855-878. doi: 10.1163/1568539X-bja10028 Summary: This study reviews the characterization of fever and sickness behavior regulated by cytokines during infection. Usage: IL-1β-saporin or unconjugated Saporin as control (icv or ip, 1.75 μg) eliminated IL-1R1-expressing cells in the
Characterization of fever and sickness behavior regulated by cytokines during infection. Read More »
Cat. #IT-01 192-IgG-SAP Long-term potentiation in the hippocampal CA3 to CA1 synapses may be induced in vivo by activation of septal cholinergic inputs. Dobryakova, Y. V., M. Y. Stepanichev, V. A. Markevich and A. P. Bolshakov (2020). Int J Neurosci: 1-9. Intracerebroventricular Administration of 192IgG-Saporin Alters the State of Microglia in the Neocortex. Volobueva, M. N., Y.
World Alzheimer’s Month – Latest publications Read More »
Audira G, Ngoc Anh NT, Ngoc Hieu BT, Malhotra N, Siregar P, Villalobos O, Villaflores OB, Ger TR, Huang JC, Chen KH, Hsiao CD (2020) Evaluation of the adverse effects of chronic exposure to donepezil (an acetylcholinesterase inhibitor) in adult zebrafish by behavioral and biochemical assessments. Biomolecules 10(9):1340. doi: 10.3390/biom10091340 PMID: 32962160 Objective: The authors
Kiguchi N, Saika F, Fukazawa Y, Matsuzaki S, Kishioka S (2020) Critical role of GRP receptor-expressing neurons in the spinal transmission of imiquimod-induced psoriatic itch. Neuropsychopharmacol Rep 40(3):287-290. doi: 10.1002/npr2.12120 PMID: 32584520 Objective: To determine whether itch-responsive GRPR⁺ neurons in the spinal dorsal horn contribute to the transmission of imiquimod (IMQ)-induced psoriatic itch. Summary: Topical