Author name: Kristen Hartman

Effects of propofol on sleep architecture and sleep-wake systems in rats

Yue XF, Wang AZ, Hou YP, Fan K (2021) Effects of propofol on sleep architecture and sleep-wake systems in rats. Behav Brain Res 411:113380. doi: 10.1016/j.bbr.2021.113380 Objective: To characterize the effects of propofol on the profile of sleep–wake states and cortical electroencephalogram (EEG) power spectral density in rats following intraperitoneal injection. Summary: The high dose […]

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TRP channels in cancer pain

de Almeida AS, Bernardes LB, Trevisan G (2021) TRP channels in cancer pain. Eur J Pharmacol 904:174185. doi: 10.1016/j.ejphar.2021.174185 PMID: 34015320 Objective: To describe the role of TRP vanilloid 1 (TRPV1) and TRP ankyrin 1 (TRPA1) involved in cancer pain mechanisms. Summary: Several studies have revealed that the administration of TRPV1 or TRPA1 agonists/antagonists and

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Baoyuan decoction (BYD) attenuates cardiac hypertrophy through ANKRD1-ERK/GATA4 pathway in heart failure after acute myocardial infarction

Meng H, Du Z, Lu W, Wang Q, Sun X, Jiang Y, Wang Y, Li C, Tu P (2021) Baoyuan decoction (BYD) attenuates cardiac hypertrophy through ANKRD1-ERK/GATA4 pathway in heart failure after acute myocardial infarction. Phytomedicine 89:153617. doi: 10.1016/j.phymed.2021.153617 PMID: 34157504 Objective: To explore whether BYD plays a protective role against heart failure (HF) by

Baoyuan decoction (BYD) attenuates cardiac hypertrophy through ANKRD1-ERK/GATA4 pathway in heart failure after acute myocardial infarction Read More »

Centrally projecting edinger-westphal nucleus in the control of sympathetic outflow and energy homeostasis

Cano G, Hernan SL, Sved AF (2021) Centrally projecting edinger-westphal nucleus in the control of sympathetic outflow and energy homeostasis. Brain Sci 11(8):1005. doi: 10.3390/brainsci11081005 Objective: To test the hypothesis that Edinger-Westphal nucleus (EWcp) integrates multimodal signals (stress, thermal, metabolic, endocrine, etc.) and modulates the sympathetic output simultaneously to multiple effector organs to maintain energy

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Injection of anti-proBDNF attenuates hippocampal-dependent learning and memory dysfunction in mice with sepsis-associated encephalopathy

Cui YH, Zhou SF, Liu Y, Wang S, Li F, Dai RP, Hu ZL, Li CQ (2021) Injection of anti-proBDNF attenuates hippocampal-dependent learning and memory dysfunction in mice with sepsis-associated encephalopathy. Front Neurosci 15:665757. doi: 10.3389/fnins.2021.665757 PMID: 34354558 Objective: To study the effects and associated mechanism of hippocampal proBDNF in a lipopolysaccharide (LPS)-induced sepsis-associated encephalopathy

Injection of anti-proBDNF attenuates hippocampal-dependent learning and memory dysfunction in mice with sepsis-associated encephalopathy Read More »

Therapeutic agent delivery across the blood-brain barrier using focused ultrasound

McMahon D, O’Reilly MA, Hynynen K (2021) Therapeutic agent delivery across the blood-brain barrier using focused ultrasound. Annu Rev Biomed Eng 23:89-113. doi: 10.1146/annurev-bioeng-062117-121238 PMID: 33752471 Summary: Review of the use of focused ultrasound, in combination with circulating microbubbles, can be used to transiently and noninvasively increase cerebrovascular permeability with a high level of spatial

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Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration

Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M (2021) Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration. Dev Cell 56(13):1917-1929.e9. doi: 10.1016/j.devcel.2021.05.016 PMID: 34129836 Objective: To investigate the molecular mechanisms regulating how basal cells contribute to adult tissue regeneration by shifting from slow cycling to

Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration Read More »

Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem

Li F, Jiang H, Shen X, Yang W, Guo C, Wang Z, Xiao M, Cui L, Luo W, Kim BS, Chen Z, Huang AJW, Liu Q (2021) Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem. Cell 184(14):3762-3773.e10. doi: 10.1016/j.cell.2021.05.017 Objective: To test the hypothesis that a neuronal population postsynaptic to nasal

Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem Read More »

The medial septum as a potential target for treating brain disorders associated with oscillopathies

Takeuchi Y, Nagy AJ, Barcsai L, Li Q, Ohsawa M, Mizuseki K, Berényi A (2021) The medial septum as a potential target for treating brain disorders associated with oscillopathies. Front Neural Circuits 15:701080. doi: 10.3389/fncir.2021.701080 Summary: The medial septum (MS) may be a potential target for treating neurological and psychiatric disorders with abnormal oscillations (oscillopathies)

The medial septum as a potential target for treating brain disorders associated with oscillopathies Read More »

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