Author name: Kristen Hartman

Mechanism of Radix Astragali and Radix Salviae Miltiorrhizae ameliorates hypertensive renal damage

Hou G, Jiang Y, Zheng Y, Zhao M, Chen Y, Ren Y, Wang C, Li W (2021) Mechanism of Radix Astragali and Radix Salviae Miltiorrhizae ameliorates hypertensive renal damage. Biomed Res Int eCollection:5598351. doi: 10.1155/2021/5598351 PMID: 33969119 Objective: To explore the mechanism of combination of Radix Astragali (RA) and Radix Salviae Miltiorrhizae (RS) ameliorating HRD […]

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Dissection and surgical approaches to the mouse jugular-nodose ganglia

Han W, de Araujo IE (2021) Dissection and surgical approaches to the mouse jugular-nodose ganglia. STAR Protocols 2(2):100474. doi: 10.1016/j.xpro.2021.100474 Usage: Injected 0.5 µl of CCK-SAP (250 ng/µl) into the R-NG of VGlut2-ires-Cre mice. Related Products: CCK-SAP (Cat. #IT-31) For complete details on the use and execution of this protocol, please refer to Han et

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Developments in understanding diffuse noxious inhibitory controls: pharmacological evidence from pre-clinical research

Kucharczyk MW, Valiente D, Bannister K (2021) Developments in understanding diffuse noxious inhibitory controls: pharmacological evidence from pre-clinical research. J Pain Res 14:1083-1095. doi: 10.2147/JPR.S258602 Summary: This review discusses the pharmacological manipulation interrogation strategies that have been used to examine the functionality of diffuse noxious inhibitory controls (DNIC) and descending control of nociception (DCN). Usage:

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Vehicle emissions-exposure alters expression of systemic and tissue-specific components of the renin-angiotensin system and promotes outcomes associated with cardiovascular disease and obesity in wild-type C57BL/6 male mice

Phipps BL, Suwannasual U, Lucero J, Mitchell NA, Lund AK (2021) Vehicle emissions-exposure alters expression of systemic and tissue-specific components of the renin-angiotensin system and promotes outcomes associated with cardiovascular disease and obesity in wild-type C57BL/6 male mice. Toxicol Rep 8:846-862. doi: 10.1016/j.toxrep.2021.04.001 PMID: 33948438 Objective: To investigate the hypothesis that exposure to engine emissions

Vehicle emissions-exposure alters expression of systemic and tissue-specific components of the renin-angiotensin system and promotes outcomes associated with cardiovascular disease and obesity in wild-type C57BL/6 male mice Read More »

Cholinergic signaling, neural excitability, and epilepsy

Wang Y, Tan B, Wang Y, Chen Z (2021) Cholinergic signaling, neural excitability, and epilepsy. Molecules 26(8):2258. doi: 10.3390/molecules26082258 Summary: In this review, the authors briefly describe the distribution of cholinergic neurons, muscarinic, and nicotinic receptors in the central nervous system and their relationship with neural excitability and epilepsy. intraventricular administration of 192-IgG-SAP, which inhibits

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GRPR/extracellular signal-regulated kinase and NPRA/extracellular signal-regulated kinase signaling pathways play a critical role in spinal transmission of chronic itch

Liu X, Wang Y, Tao T, Zeng L, Wang D, Wen Y, Li Y, Zhao Z, Tao A (2021) GRPR/extracellular signal-regulated kinase and NPRA/extracellular signal-regulated kinase signaling pathways play a critical role in spinal transmission of chronic itch. J Invest Dermatol 141(4):863-873. doi: 10.1016/j.jid.2020.09.008 Summary: This study investigates whether there are certain key signaling molecules

GRPR/extracellular signal-regulated kinase and NPRA/extracellular signal-regulated kinase signaling pathways play a critical role in spinal transmission of chronic itch Read More »

Striatal cholinergic interneurons exert inhibition on competing default behaviours controlled by the nucleus accumbens and dorsolateral striatum.

Ashkenazi SL, Polis B, David O, Morris G (2021) Striatal cholinergic interneurons exert inhibition on competing default behaviours controlled by the nucleus accumbens and dorsolateral striatum. Eur J Neurosci 53(7):2078-2089. doi: 10.1111/ejn.14873 Objective: To determine whether cholinergic interneurons contribute to the competition between both ventral and dorsolateral control systems. Summary: Findings indicate a central role

Striatal cholinergic interneurons exert inhibition on competing default behaviours controlled by the nucleus accumbens and dorsolateral striatum. Read More »

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