Author name: Kristen Hartman

Silveira DC, Cha BH, Holmes GL (2002) Effects of lesions of basal forebrain cholinergic neurons in newborn rats on susceptibility to seizures. Dev Brain Res 139:277-283. doi: 10.1016/s0165-3806(02)00586-2 Summary: It has previously been shown that adult rats treated with the cholinergic lesioning agent 192-Saporin (Cat. #IT-01) display increased susceptibility to generalized seizures. Here, the authors […]

Helm KA, Han JS, Gallagher M (2002) Effects of cholinergic lesions produced by infusions of 192 IgG-saporin on glucocorticoid receptor mRNA expression in hippocampus and medial prefrontal cortex of the rat. Neuroscience 115(3):765-774. doi: 10.1016/s0306-4522(02)00487-6 Summary: The authors investigated the loss of cholinergic support from the basal forebrain, a hallmark of aging, on glucocorticoid receptor

Riley J, Lin LH, Chianca DA, Talman WT (2002) Ablation of NK1 receptors in rat nucleus tractus solitarii blocks baroreflexes. Hypertension 40(6):823-826. doi: 10.1161/01.hyp.0000042089.34004.cf Summary: Stimulation of arterial baroreflexes releases the neuropeptide substance P (SP) from vagal afferent nerves within the nucleus tractus solitarii. To ascertain whether the neurons taking up this SP are critical

Ricceri L, Hohmann C, Berger-Sweeney J (2002) Early neonatal 192 IgG saporin induces learning impairments and disrupts cortical morphogenesis in rats. Brain Res 954(2):160-172. doi: 10.1016/s0006-8993(02)03172-4 Summary: Previous data have shown that cholinergic lesions on postnatal day (pnd) 7 in rats produce learning impairments on pnd 15. Using 0.2 µg injections of 192-Saporin (Cat. #IT-01)