Author name: Kristen Hartman

McGaughy JA, Rubin S, Stollstorff M, Baxter MG, Eichenbaum HB (2002) 192 IgG-saporin-induced cortical, cholinergic deafferentation in rats produces a dissociation in the function of prelimbic/infralimbic and orbitofrontal cortex in an attentional set-shifting task. Neuroscience 2002 Abstracts 674.4. Society for Neuroscience, Orlando, FL. Summary: Converging data support the hypothesis that cholinergic afferents to the cortex […]

Sarter MF, Draut A, Herzog CD, Bruno JP (2002) Effects of septohippocampal cholinergic deafferentation on attention and learning. Neuroscience 2002 Abstracts 674.8. Society for Neuroscience, Orlando, FL. Summary: In contrast to the extensively studied attentional functions mediated via basal forebrain corticopetal cholinergic projections, the role of septohippocampal cholinergic projections in attention and memory have remained

Rudick CN, Gibbs RB, Woolley CS (2002) Estrogen-induced disinhibition of hippocampal CA1 pyramidal cells depends on basal forebrain cholinergic neurons. Neuroscience 2002 Abstracts 740.6. Society for Neuroscience, Orlando, FL. Summary: Estrogen (E) increases dendritic spine and synapse density on hippocampal pyramidal cells, both in vivo and in vitro. In both cases, the increase in spine/synapse

Sherren N, Pappas BA (2002) Neonatal dopamine lesions: Cognitive impairment or hyper-sensitivity to stress. Neuroscience 2002 Abstracts 782.19. Society for Neuroscience, Orlando, FL. Summary: Neonatal rat pups given a selective cholinergic immunotoxin exhibit large reductions in cortical (30-70%) and hippocampal (75%) choline acetyltransferase (ChAT) activity which persist into adulthood. However these rats do not show

Fraley GS (2002) Role of hindbrain catecholaminergic afferents to the medial hypothalamus in the regulation of penile reflexes in the rat. Neuroscience 2002 Abstracts 681.4. Society for Neuroscience, Orlando, FL. Summary: The use of ex copula erections, or reflexive erections, has been used for decades in the study of the central pathways and neuroendocrinology of

Fox K, Wolff I, Curtis A, Pernar L, Van Bockstaele EJ, Valentino RJ (2002) Multiple lines of evidence for the existence of corticotropin-releasing factor (CRF) receptors on locus coeruleus (LC) neurons. Neuroscience 2002 Abstracts 637.9. Society for Neuroscience, Orlando, FL. Summary: Several physiological and anatomical findings suggest that CRF acts as a neuromodulator of LC

Beach TG, Potter PE, Sue LI, Fisher A, Scott S, Layne KJ, Newell AJ, Roher AE, Walker DG (2002) Cerebral abeta deposition induced by cortical cholinergic deafferentation is reduced by cholinergic therapy. Neuroscience 2002 Abstracts 722.9. Society for Neuroscience, Orlando, FL. Summary: We have previously shown that cortical cholinergic deafferentation in rabbits results in cerebral

Schaevitz LR, Baxter MG, Stearns NA, Huang YY, Lappi DA, Berger-Sweeney J (2002) The efficacy of intraparenchymal anti-p75 immunotoxin on medial septal cholinergic neurons in mice. Neuroscience 2002 Abstracts 778.11. Society for Neuroscience, Orlando, FL. Summary: We have shown previously that anti-murine-p75-SAP (saporin conjugated to a rat monoclonal antibody against the mouse p75 nerve growth

Gerashchenko D, Blanco-Centurion C, Shiromani PJ (2002) Hypocretin2-saporin (HCRT2-SAP) lesions of the lateral hypothalamus does not affect the entrained or free-running rhythm of core body temperature. Neuroscience 2002 Abstracts 776.2. Society for Neuroscience, Orlando, FL. Summary: Hypocretin (HCRT)neurons are present only in the lateral hypothalamus (LH) from where they project heavily to major arousal centers.