Author name: Kristen Hartman

Jasmin L, Arsenault P, Ohara PT, Marchand S (2000) Chronic noradrenergic spinal denervation in rats does not produce long-term hyperalgesia. Neuroscience 2000 Abstracts 243.7. Society for Neuroscience, New Orleans, LA. Summary: Pharmacological studies have established that noradrenaline tonically inhibits spinal nociceptive transmission. We tested the hypothesis that chronically decreasing spinal noradrenaline would result in a […]

Vierck CJ, Belford PM, Iqbal MA, Camara C, Kline RH, Lappi DA, Wiley RG (2000) Altered operant and reflex responses to noxious heat in rats with central noradrenergic lesions using antiDßH-saporin. Neuroscience 2000 Abstracts 247.10. Society for Neuroscience, New Orleans, LA. Summary: We sought to determine effects of a selective lesion of pontine NA neurons

Schreihofer AM, Stornetta RL, Guyenet PG (2000) Regulation of sympathetic vasomotor tone and arterial pressure by the rostral ventrolateral medulla after elimination of C1 neurons in rat. Neuroscience 2000 Abstracts 310.7. Society for Neuroscience, New Orleans, LA. Summary: The rostral ventrolateral medulla (RVLM) tonically stimulates sympathetic preganglionic neurons to maintain arterial pressure (AP). Although the

Ciriello J, Rosas-Arellano MP, Solano-Flores LP (2000) Intrathecal injections of saporin conjugated substance-P alter the development of renal hypertension. Neuroscience 2000 Abstracts 310.2. Society for Neuroscience, New Orleans, LA. Summary: We have recently shown that there is an up-regulation of mRNA encoding Substance-P (SP) in dorsal root ganglia in the two kidney, one clip (2K1C)

Vulchanova L, Olson TH, Elde R, Honda CN (2000) Role of IB4-binding sensory neurons in the effects of intradermal capsaicin injection. Neuroscience 2000 Abstracts 212.7. Society for Neuroscience, New Orleans, LA. Summary: We have shown previously that a unilateral injection of a conjugate of the lectin IB4 and the toxin saporin (IB4-SAP) into sciatic nerve

Martin JL, Sloviter RS (2000) Focal hippocampal hyperexcitability after focal interneuron ablation in the rat by substance P-saporin. Neuroscience 2000 Abstracts 389.13. Society for Neuroscience, New Orleans, LA. Summary: Hyperexcitability after prolonged seizures or head trauma may result from interneuron malfunction or loss; but a causal relationship is in doubt because global insults produce widespread

Burgess SE, Vanderah TW, Mantyh PW, Malan Jr TP, Ossipov MH, Lappi D, Lai J, Porreca F (2000) Dermorphin-saporin targets tonic descending facilitation in the rostral ventromedial medulla to block and reverse neuropathic pain. Neuroscience 2000 Abstracts 243.6. Society for Neuroscience, New Orleans, LA. Summary: The hypothesis that chronic pain from L5/L6 spinal nerve ligation

Miller SA, Lappi DA, Wiley RG (2000) Intrathecal dermorphin-saporin decreases morphine effect in hotplate algesia testing. Neuroscience 2000 Abstracts 212.8. Society for Neuroscience, New Orleans, LA. Summary: The targeted cytotoxin, dermorphin-saporin, selectively destroys cells expressing MOR. In the present study, we gave dermorphin-saporin by lumbar i.t. injection and sought to determine if destroying dorsal horn

Easton A, Ridley RM, Baker HF, Gaffan D (2000) Crossed unilateral lesions of the cholinergic basal forebrain (by me20.4IgG-saporin) and fornix from inferior temporal cortex produce severe learning impairments in rhesus monkeys. Neuroscience 2000 Abstracts 205.8. Society for Neuroscience, New Orleans, LA. Summary: Section of the anterior temporal stem, amygdala and fornix in monkeys results

Bitner RS, Nikkel AL, Decker MW (2000) Immunohistochemical detection of alpha-7 nicotinic receptor expression by two distinct cell types in the dorsal raphe and locus coeruleus of rat. Neuroscience 2000 Abstracts 41.7. Society for Neuroscience, New Orleans, LA. Summary: The α7 nicotinic acetylcholine receptor (nAChR) subunit can be assembled to form a homomeric-pentamer with high