Author name: Kristen Hartman

Dose-dependent effects of intrathecal substance P-saporin and SSP-saporin.

Wiley RG, Kline IV RH, Lappi DA (2001) Dose-dependent effects of intrathecal substance P-saporin and SSP-saporin. Neuroscience 2001 Abstracts 281.11. Society for Neuroscience, San Diego, CA. Summary: Selective destruction of lamina I dorsal horn neurons expressing the neurokinin-1 receptor (NK-1R) can attenuate responses to capsaicin injection and thermal hyperalgesia/mechanical allodynia in models of inflammatory, persistent […]

Dose-dependent effects of intrathecal substance P-saporin and SSP-saporin. Read More »

Hypocretin-saporin (Hcrt-sap) as a tool to examine hypocretin function.

Gerashchenko D, Kohls MD, Greco MA, Waleh NS, Salin-Pascual R, Kilduff TS, Lappi DA, Shiromani PJ (2001) Hypocretin-saporin (Hcrt-sap) as a tool to examine hypocretin function. Neuroscience 2001 Abstracts 410.7. Society for Neuroscience, San Diego, CA. Summary: The hypocretin (Hcrt) peptides are linked to narcolepsy. Humans with narcolepsy have decreased numbers of Hcrt neurons and

Hypocretin-saporin (Hcrt-sap) as a tool to examine hypocretin function. Read More »

Light- and food-entrained circadian rhythms in rats with neurotoxic lesions of hypocretin cells.

Mistlberger RE, Antle MC, Jones M, Kilduff TS (2001) Light- and food-entrained circadian rhythms in rats with neurotoxic lesions of hypocretin cells. Neuroscience 2001 Abstracts 410.8. Society for Neuroscience, San Diego, CA. Summary: The hypocretins (Hcrt1 & 2) are lateral hypothalamic (LH) neuropeptides implicated in the regulation of feeding and sleep-wake states. Hcrt lesions attenuate

Light- and food-entrained circadian rhythms in rats with neurotoxic lesions of hypocretin cells. Read More »

Hypocretin B-saporin lesions of the brainstem increase rem sleep at night.

Blanco-Centurion CA, Salin-Pascual RJ, Gerashchenko D, Greco MA, Shiromani PJ (2001) Hypocretin B-saporin lesions of the brainstem increase rem sleep at night. Neuroscience 2001 Abstracts 410.9. Society for Neuroscience, San Diego, CA. Summary: Loss of hypocretin (Hcrt) neurons has been linked to narcolepsy. These neurons project widely throughout brain, but it is not known which

Hypocretin B-saporin lesions of the brainstem increase rem sleep at night. Read More »

Interactions between partial cortical cholinergic deafferentation and aging on sustained attention performance in rats.

Burk JA, Herzog CD, Porter MC, Mahoney J, Bruno JP, Sarter M (2001) Interactions between partial cortical cholinergic deafferentation and aging on sustained attention performance in rats. Neuroscience 2001 Abstracts 202.5. Society for Neuroscience, San Diego, CA. Summary: Previous studies have provided only limited support for the idea that aging alone impairs the functions of

Interactions between partial cortical cholinergic deafferentation and aging on sustained attention performance in rats. Read More »

Targeted destruction of A2/C2 catecholamine neurons alters hypothalamic responses to vagal stimulation.

Rinaman L, Wonders CP (2001) Targeted destruction of A2/C2 catecholamine neurons alters hypothalamic responses to vagal stimulation. Neuroscience 2001 Abstracts 131.4. Society for Neuroscience, San Diego, CA. Summary: Central catecholamine (CA) pathways participate in viscerosensory modulation of hypothalamic neuroendocrine function. Different brainstem CA cell groups may relay different types of viscerosensory signals to different classes

Targeted destruction of A2/C2 catecholamine neurons alters hypothalamic responses to vagal stimulation. Read More »

Intrathecal infusion of substance P-saporin ablates substance p receptor expressing neurons in the dorsal horn of the spinal cord and attenuates bone cancer pain.

Luger NM, Sabino MC, Schwei MJ, Rogers SD, Pomonis JD, Keyser CP, Mach DB, Salak-Johnson J, Clohisy DR, Mantyh PW (2001) Intrathecal infusion of substance P-saporin ablates substance p receptor expressing neurons in the dorsal horn of the spinal cord and attenuates bone cancer pain. Neuroscience 2001 Abstracts 55.4. Society for Neuroscience, San Diego, CA.

Intrathecal infusion of substance P-saporin ablates substance p receptor expressing neurons in the dorsal horn of the spinal cord and attenuates bone cancer pain. Read More »

NK1-expressing neurons critical for morphine reward behaviors in mice: C-fos expression and ablation of NK1-expressing neurons.

Gadd CA, Murtra P, Hall CN, Gana M, Webber MJ, De Felipe C, Hunt SP (2001) NK1-expressing neurons critical for morphine reward behaviors in mice: C-fos expression and ablation of NK1-expressing neurons. Neuroscience 2001 Abstracts 224.13. Society for Neuroscience, San Diego, CA. Summary: We have previously shown using conditioned place preference (CPP) that mice lacking

NK1-expressing neurons critical for morphine reward behaviors in mice: C-fos expression and ablation of NK1-expressing neurons. Read More »

Capsaicin-sensitive inhibitory pathway in rat spinal cord dorsal horn.

Gu JG, Nakatsuka T, Tanaka E, Takeda D, Jennifer LX (2001) Capsaicin-sensitive inhibitory pathway in rat spinal cord dorsal horn. Neuroscience 2001 Abstracts 158.13. Society for Neuroscience, San Diego, CA. Summary: The inhibitory system in the spinal cord plays an important role in regulating nociceptive sensory inputs. Here we examined inhibitory synaptic activity in lamina

Capsaicin-sensitive inhibitory pathway in rat spinal cord dorsal horn. Read More »

α,β-methylene ATP sensitive P2X receptor mediated enhancement of glutamate release from the central terminals of Aδ primary afferents onto lamina V neurons in rat spinal cord.

Nakatsuka T, Takeda D, Gu JG (2001) α,β-methylene ATP sensitive P2X receptor mediated enhancement of glutamate release from the central terminals of Aδ primary afferents onto lamina V neurons in rat spinal cord. Neuroscience 2001 Abstracts 158.16. Society for Neuroscience, San Diego, CA. Summary: We examined the role of αβmATP-sensitive P2X receptors in modulating glutamate

α,β-methylene ATP sensitive P2X receptor mediated enhancement of glutamate release from the central terminals of Aδ primary afferents onto lamina V neurons in rat spinal cord. Read More »

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