Targeted SAP conjugates are powerful and specific lesioning agents used in the technique known as Molecular Surgery ZAP conjugates are non-targeted saporin conjugates that “piggyback” on to your primary targeting agent Controls are a vital part of the scientific procedure. These control conjugates are the same molecular weight, consist of similar, comparable materials and are […]
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Beta Program Video An introduction to our Beta Product Program. What is it and what are the benefits?
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Question: We have been using your human fab-pHast (PH-01) product for a while now and are very happy with the results in our imaging applications (we have seen signal to noise of over 70k). However I have recently tried running a black bottom plate on a plate reader, same set up, and am getting a
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Vringer M, Zhou J, Gool JK, Bijlenga D, Lammers GJ, Fronczek R, Schinkelshoek MS (2024) Recent insights into the pathophysiology of narcolepsy type 1. Sleep Med Rev 78:101993. doi: 10.1016/j.smrv.2024.101993 PMID: 39241492 Objective: To focus on recent insights into Narcolepsy type 1 (NT1) pathophysiology, discussing structural and functional changes, immune system involvement, genetic findings, and
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Wang D, Wei SN, Zhang L, Lang ZC, Wang SN, Cheng B, Lu Y, Wang X, Wang W, Li FS, Zhang H (2024) Impaired basal forebrain cholinergic neuron gdnf signaling contributes to perioperative sleep deprivation–induced chronicity of postsurgical pain in mice through regulating cholinergic neuronal activity, apoptosis, and autophagy. CNS Nerusci Ther doi: 10.1111/cns.70147 PMID:
Lewis RD, Keilholz AN, Smith CL, Burd EA, Nichols NL (2024) Spinal TNF-α receptor 1 is differentially required for phrenic long-term facilitation (pLTF) over the course of motor neuron death in adult rats. Front Physiol 15 doi: 10.3389/fphys.2024.1488951 PMID: 39703667 Objective: To study the impact motor neuron death has on the output of surviving phrenic
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Morishata Y, Fuentes I, Gonzalez-Salinas S, Favate J, Mejaes J, Zushida K, Nishi A, Hevi C, Goldsmith N, Buyske S, Sillivan SE, Miller CA, Kandel ER, Uchida S, Shah P, Alarcon JM, Barker DJ, Shumyatsky GP (2024) Dopamine release and dopamine-related gene expression in the amygdala are modulated by the gastrin-releasing peptide in opposite directions
The p75 neurotrophin receptor (p75NTR), also known as the low affinity nerve growth factor receptor, binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. It is a 75kDa membrane-spanning glycoprotein lacking intrinsic tyrosine kinase activity. p75 is expressed in various parts of the brain, notably in the basal forebrain by cholinergic
NGFR Antibody Videos An introduction to NGFR Antibodies. What are they and how can you use them? More languages available More languages available keywords: P75NTR, NGFR, Alzheimer’s Disease, dementia, basal forebrain, animal model, neuronal loss, low affinity nerve growth factor, neurotrophin receptors, mesenchyme, Anti-NGFR, Anti-Nerve Growth Factor, 192-IgG, p75, brain, neuroscience
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