Author name: Kristen Hartman

Long-term plastic changes in galanin innervation in the rat basal forebrain.

Hartonian I, Mufson EJ, de Lacalle S (2002) Long-term plastic changes in galanin innervation in the rat basal forebrain. Neuroscience 115(3):787-795. doi: 10.1016/s0306-4522(02)00453-0 Summary: One hallmark of Alzheimer’s disease is the hyperinnervation of surviving cholinergic basal forebrain neurons with galanin-IR fibers. This may exacerbate the cholinergic deficit. The authors injected 192-Saporin (140 nl of 0.075 […]

Long-term plastic changes in galanin innervation in the rat basal forebrain. Read More »

Effects of cholinergic lesions produced by infusions of 192 IgG-saporin on glucocorticoid receptor mRNA expression in hippocampus and medial prefrontal cortex of the rat.

Helm KA, Han JS, Gallagher M (2002) Effects of cholinergic lesions produced by infusions of 192 IgG-saporin on glucocorticoid receptor mRNA expression in hippocampus and medial prefrontal cortex of the rat. Neuroscience 115(3):765-774. doi: 10.1016/s0306-4522(02)00487-6 Summary: The authors investigated the loss of cholinergic support from the basal forebrain, a hallmark of aging, on glucocorticoid receptor

Effects of cholinergic lesions produced by infusions of 192 IgG-saporin on glucocorticoid receptor mRNA expression in hippocampus and medial prefrontal cortex of the rat. Read More »

Ablation of NK1 receptors in rat nucleus tractus solitarii blocks baroreflexes.

Riley J, Lin LH, Chianca DA, Talman WT (2002) Ablation of NK1 receptors in rat nucleus tractus solitarii blocks baroreflexes. Hypertension 40(6):823-826. doi: 10.1161/01.hyp.0000042089.34004.cf Summary: Stimulation of arterial baroreflexes releases the neuropeptide substance P (SP) from vagal afferent nerves within the nucleus tractus solitarii. To ascertain whether the neurons taking up this SP are critical

Ablation of NK1 receptors in rat nucleus tractus solitarii blocks baroreflexes. Read More »

Early neonatal 192 IgG saporin induces learning impairments and disrupts cortical morphogenesis in rats.

Ricceri L, Hohmann C, Berger-Sweeney J (2002) Early neonatal 192 IgG saporin induces learning impairments and disrupts cortical morphogenesis in rats. Brain Res 954(2):160-172. doi: 10.1016/s0006-8993(02)03172-4 Summary: Previous data have shown that cholinergic lesions on postnatal day (pnd) 7 in rats produce learning impairments on pnd 15. Using 0.2 µg injections of 192-Saporin (Cat. #IT-01)

Early neonatal 192 IgG saporin induces learning impairments and disrupts cortical morphogenesis in rats. Read More »

Effect of selective cholinergic lesioning of basal forebrain with 192 IgG-saporin on neurotransmitter concentrations in hippocampus of rat

Nagle RA, Liberatore MA, Zombon NJ, Pokala VN, Li PK, Pokala VN, Johnson DA (2002) Effect of selective cholinergic lesioning of basal forebrain with 192 IgG-saporin on neurotransmitter concentrations in hippocampus of rat. Neuroscience 2002 Abstracts 880.6. Society for Neuroscience, Orlando, FL. Summary: In vivo microdialysis techniques were used to examine the effects of lesioning

Effect of selective cholinergic lesioning of basal forebrain with 192 IgG-saporin on neurotransmitter concentrations in hippocampus of rat Read More »

Immunotoxic lesions of ascending catechoalminergic afferents abolish the CRH gene transcriptional response to 2-deoxyglucose in the rat paraventricular nucleus

Watts AG, Sanchez-Watts G, Dinh TT, Ritter S (2002) Immunotoxic lesions of ascending catechoalminergic afferents abolish the CRH gene transcriptional response to 2-deoxyglucose in the rat paraventricular nucleus. Neuroscience 2002 Abstracts 865.2. Society for Neuroscience, Orlando, FL. Summary: CRH neurons in the medial parvicellular (mp) part of the paraventricular nucleus (PVH) are critical for the

Immunotoxic lesions of ascending catechoalminergic afferents abolish the CRH gene transcriptional response to 2-deoxyglucose in the rat paraventricular nucleus Read More »

Immunotoxic lesion of catecholamine afferents to paraventricular hypothalamus (PVH) impairs the corticosterone response to glucoprivation but not the basal secretory rhythm or response to swim stress

Ritter S, Dinh TT, Pedrow C, Roellich K (2002) Immunotoxic lesion of catecholamine afferents to paraventricular hypothalamus (PVH) impairs the corticosterone response to glucoprivation but not the basal secretory rhythm or response to swim stress. Neuroscience 2002 Abstracts 865.4. Society for Neuroscience, Orlando, FL. Summary: Catecholamine afferents from the hindbrain densely innervate the medial parvicellular

Immunotoxic lesion of catecholamine afferents to paraventricular hypothalamus (PVH) impairs the corticosterone response to glucoprivation but not the basal secretory rhythm or response to swim stress Read More »

Neurokinin-1 receptor immunoreactive (NK1R-ir) neurons control caudal ventrolateral medulla (VLM) gabaergic depressor neurons

Wang H, Guyenet PG (2002) Neurokinin-1 receptor immunoreactive (NK1R-ir) neurons control caudal ventrolateral medulla (VLM) gabaergic depressor neurons. Neuroscience 2002 Abstracts 862.4. Society for Neuroscience, Orlando, FL. Summary: Depressor responses to injection of DL-homocysteic acid (DLH) into the caudal VLM are attenuated after selective unilateral lesion of the NK1R-ir cells of the VLM with a

Neurokinin-1 receptor immunoreactive (NK1R-ir) neurons control caudal ventrolateral medulla (VLM) gabaergic depressor neurons Read More »

The efficacy of intraparenchymal anti-p75 immunotoxin on medial septal cholinergic neurons in mice

Schaevitz LR, Baxter MG, Stearns NA, Huang YY, Lappi DA, Berger-Sweeney J (2002) The efficacy of intraparenchymal anti-p75 immunotoxin on medial septal cholinergic neurons in mice. Neuroscience 2002 Abstracts 778.11. Society for Neuroscience, Orlando, FL. Summary: We have shown previously that anti-murine-p75-SAP (saporin conjugated to a rat monoclonal antibody against the mouse p75 nerve growth

The efficacy of intraparenchymal anti-p75 immunotoxin on medial septal cholinergic neurons in mice Read More »

Hypocretin2-saporin (HCRT2-SAP) lesions of the lateral hypothalamus does not affect the entrained or free-running rhythm of core body temperature.

Gerashchenko D, Blanco-Centurion C, Shiromani PJ (2002) Hypocretin2-saporin (HCRT2-SAP) lesions of the lateral hypothalamus does not affect the entrained or free-running rhythm of core body temperature. Neuroscience 2002 Abstracts 776.2. Society for Neuroscience, Orlando, FL. Summary: Hypocretin (HCRT)neurons are present only in the lateral hypothalamus (LH) from where they project heavily to major arousal centers.

Hypocretin2-saporin (HCRT2-SAP) lesions of the lateral hypothalamus does not affect the entrained or free-running rhythm of core body temperature. Read More »

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