Author name: Kristen Hartman

ß1 adrenergic antagonist effect on brain muscarinic cholinergic receptors

Harrell LE, Parsons DS, Conger K, Kolasa K (2002) ß1 adrenergic antagonist effect on brain muscarinic cholinergic receptors. Neuroscience 2002 Abstracts 685.13. Society for Neuroscience, Orlando, FL. Summary: Degeneration of basal forebrain cholinergic system and sympathetic ingrowth appear to be pathologic changes in Alzheimer’s Disease (AD). An imbalance between these systems may mediate cognitive deficit […]

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Estrogen-induced disinhibition of hippocampal CA1 pyramidal cells depends on basal forebrain cholinergic neurons

Rudick CN, Gibbs RB, Woolley CS (2002) Estrogen-induced disinhibition of hippocampal CA1 pyramidal cells depends on basal forebrain cholinergic neurons. Neuroscience 2002 Abstracts 740.6. Society for Neuroscience, Orlando, FL. Summary: Estrogen (E) increases dendritic spine and synapse density on hippocampal pyramidal cells, both in vivo and in vitro. In both cases, the increase in spine/synapse

Estrogen-induced disinhibition of hippocampal CA1 pyramidal cells depends on basal forebrain cholinergic neurons Read More »

Neonatal dopamine lesions: Cognitive impairment or hyper-sensitivity to stress

Sherren N, Pappas BA (2002) Neonatal dopamine lesions: Cognitive impairment or hyper-sensitivity to stress. Neuroscience 2002 Abstracts 782.19. Society for Neuroscience, Orlando, FL. Summary: Neonatal rat pups given a selective cholinergic immunotoxin exhibit large reductions in cortical (30-70%) and hippocampal (75%) choline acetyltransferase (ChAT) activity which persist into adulthood. However these rats do not show

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Role of hindbrain catecholaminergic afferents to the medial hypothalamus in the regulation of penile reflexes in the rat

Fraley GS (2002) Role of hindbrain catecholaminergic afferents to the medial hypothalamus in the regulation of penile reflexes in the rat. Neuroscience 2002 Abstracts 681.4. Society for Neuroscience, Orlando, FL. Summary: The use of ex copula erections, or reflexive erections, has been used for decades in the study of the central pathways and neuroendocrinology of

Role of hindbrain catecholaminergic afferents to the medial hypothalamus in the regulation of penile reflexes in the rat Read More »

Multiple lines of evidence for the existence of corticotropin-releasing factor (CRF) receptors on locus coeruleus (LC) neurons

Fox K, Wolff I, Curtis A, Pernar L, Van Bockstaele EJ, Valentino RJ (2002) Multiple lines of evidence for the existence of corticotropin-releasing factor (CRF) receptors on locus coeruleus (LC) neurons. Neuroscience 2002 Abstracts 637.9. Society for Neuroscience, Orlando, FL. Summary: Several physiological and anatomical findings suggest that CRF acts as a neuromodulator of LC

Multiple lines of evidence for the existence of corticotropin-releasing factor (CRF) receptors on locus coeruleus (LC) neurons Read More »

Cerebral abeta deposition induced by cortical cholinergic deafferentation is reduced by cholinergic therapy

Beach TG, Potter PE, Sue LI, Fisher A, Scott S, Layne KJ, Newell AJ, Roher AE, Walker DG (2002) Cerebral abeta deposition induced by cortical cholinergic deafferentation is reduced by cholinergic therapy. Neuroscience 2002 Abstracts 722.9. Society for Neuroscience, Orlando, FL. Summary: We have previously shown that cortical cholinergic deafferentation in rabbits results in cerebral

Cerebral abeta deposition induced by cortical cholinergic deafferentation is reduced by cholinergic therapy Read More »

The efficacy of intraparenchymal anti-p75 immunotoxin on medial septal cholinergic neurons in mice

Schaevitz LR, Baxter MG, Stearns NA, Huang YY, Lappi DA, Berger-Sweeney J (2002) The efficacy of intraparenchymal anti-p75 immunotoxin on medial septal cholinergic neurons in mice. Neuroscience 2002 Abstracts 778.11. Society for Neuroscience, Orlando, FL. Summary: We have shown previously that anti-murine-p75-SAP (saporin conjugated to a rat monoclonal antibody against the mouse p75 nerve growth

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Hypocretin2-saporin (HCRT2-SAP) lesions of the lateral hypothalamus does not affect the entrained or free-running rhythm of core body temperature.

Gerashchenko D, Blanco-Centurion C, Shiromani PJ (2002) Hypocretin2-saporin (HCRT2-SAP) lesions of the lateral hypothalamus does not affect the entrained or free-running rhythm of core body temperature. Neuroscience 2002 Abstracts 776.2. Society for Neuroscience, Orlando, FL. Summary: Hypocretin (HCRT)neurons are present only in the lateral hypothalamus (LH) from where they project heavily to major arousal centers.

Hypocretin2-saporin (HCRT2-SAP) lesions of the lateral hypothalamus does not affect the entrained or free-running rhythm of core body temperature. Read More »

Subtypes of substance P receptor immunoreactive interneurons in the basolateral amygdala

Mania I, Levita L, Rainnie DG (2002) Subtypes of substance P receptor immunoreactive interneurons in the basolateral amygdala. Neuroscience 2002 Abstracts 637.8. Society for Neuroscience, Orlando, FL. Summary: Neurotoxic lesions of substance P receptor immunoreactive (SPR-IR) interneurons in the basolateral amygdala (BLA) using SP-saporin reduce anxiety related behavior. These lesions might provide a way to

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Developmental regulation of GABA Receptor subunits requires subplate neurons.

Kanold PO, Shatz CJ (2002) Developmental regulation of GABA Receptor subunits requires subplate neurons. Neuroscience 2002 Abstracts 530.11. Society for Neuroscience, Orlando, FL. Summary: Subplate neurons (SP) are required for formation and patterning of thalamocortical connections. In visual cortex, SP ablation before the onset of the critical period, but when LGN axons are already in

Developmental regulation of GABA Receptor subunits requires subplate neurons. Read More »

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