Author name: Kristen Hartman

Hindbrain catecholamine neurons control multiple glucoregulatory responses.

Ritter S, Dinh TT, Li AJ (2006) Hindbrain catecholamine neurons control multiple glucoregulatory responses. Physiol Behav 89(4):490-500. doi: 10.1016/j.physbeh.2006.05.036 Summary: Glucose deficit evokes many responses in the brain. Recently these workers have been focusing on mechanisms eliciting glucoregulatory responses; the focus has settled on catecholaminergic neurons in the hindbrain. In a series of experiments rats […]

Hindbrain catecholamine neurons control multiple glucoregulatory responses. Read More »

Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways.

Vera-Portocarrero LP, Zhang ET, King T, Ossipov MH, Vanderah TW, Lai J, Porreca F (2007) Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways. Pain 129:35-45. doi: 10.1016/j.pain.2006.09.033 Summary: Administration of opioids can induce hyperalgesia in humans and other mammals. In this work the authors examined the role

Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways. Read More »

Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine

Estève MA, Carré M, Bourgarel-Rey V, Kruczynski A, Raspaglio G, Ferlini C, Braguer D (2006) Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine. Mol Cancer Ther 5(11):2824-2833. doi: 10.1158/1535-7163.MCT-06-0277 PMID: 17121929 Related Products: Antibody to Detyrosinated Alpha Tubulin (AA10 (1A11)) (Cat. #AB-V42)

Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine Read More »

The nuclear DNA repair protein Ku70/80 is a tumor-associated antigen displaying rapid receptor mediated endocytosis.

Fransson J, Borrebaeck CA (2006) The nuclear DNA repair protein Ku70/80 is a tumor-associated antigen displaying rapid receptor mediated endocytosis. Int J Cancer 119(10):2492-2496. doi: 10.1002/ijc.22212 Summary: The protein Ku70/80 is expressed in the nucleus of all cells. Tumor cell lines, however, have been shown to express Ku70/80 on the cell surface. In this study,

The nuclear DNA repair protein Ku70/80 is a tumor-associated antigen displaying rapid receptor mediated endocytosis. Read More »

Ablation of NK(1) receptor bearing neurons in the nucleus of the solitary tract blunts cardiovascular reflexes in awake rats.

Abdala AP, Schoorlemmer GH, Colombari E (2006) Ablation of NK(1) receptor bearing neurons in the nucleus of the solitary tract blunts cardiovascular reflexes in awake rats. Brain Res 1119(1):165-173. doi: 10.1016/j.brainres.2006.08.059 Summary: Cardiovascular function is largely controlled by the nucleus of the tractus solitarius (NTS). This work focuses on the baroreflex, cardiopulmonary chemoreflex, and arterial

Ablation of NK(1) receptor bearing neurons in the nucleus of the solitary tract blunts cardiovascular reflexes in awake rats. Read More »

Selective depletion of cortical noradrenalin by anti-dopamine beta-hydroxylase-saporin impairs attentional function and enhances the effects of guanfacine in the rat.

Milstein JA, Lehmann O, Theobald DE, Dalley JW, Robbins TW (2007) Selective depletion of cortical noradrenalin by anti-dopamine beta-hydroxylase-saporin impairs attentional function and enhances the effects of guanfacine in the rat. Psychopharmacology (Berl) 190(1):51-63. doi: 10.1007/s00213-006-0594-x Summary: Building on previous work, the authors examined the effect of cortical noradrenalin depletion on a reaction time task.

Selective depletion of cortical noradrenalin by anti-dopamine beta-hydroxylase-saporin impairs attentional function and enhances the effects of guanfacine in the rat. Read More »

Role of catecholaminergic neurons of the caudal ventrolateral medulla in cardiovascular responses induced by acute changes in circulating volume in rats.

Pedrino GR, Maurino I, de Almeida Colombari DS, Cravo SL (2006) Role of catecholaminergic neurons of the caudal ventrolateral medulla in cardiovascular responses induced by acute changes in circulating volume in rats. Exp Physiol 91(6):995-1005. doi: 10.1113/expphysiol.2006.034611 Summary: Catecholaminergic neurons in the caudal ventrolateral medulla (CVLM) are thought to help regulate body fluid homeostasis and

Role of catecholaminergic neurons of the caudal ventrolateral medulla in cardiovascular responses induced by acute changes in circulating volume in rats. Read More »

Effect of selective cholinergic denervation on the serotonergic system: implications for learning and memory.

Garcia-Alloza M, Zaldua N, Diez-Ariza M, Marcos B, Lasheras B, Javier Gil-Bea F, Ramirez MJ (2006) Effect of selective cholinergic denervation on the serotonergic system: implications for learning and memory. J Neuropathol Exp Neurol 65(11):1074-1081. doi: 10.1097/01.jnen.0000240469.20167.89 Summary: The authors compared two lesioning methods using 192-Saporin (Cat. #IT-01) to examine the role of the serotonergic

Effect of selective cholinergic denervation on the serotonergic system: implications for learning and memory. Read More »

Noradrenergic inputs to the bed nucleus of the stria terminalis and paraventricular nucleus of the hypothalamus underlie hypothalamic-pituitary-adrenal axis but not hypophagic or conditioned avoidance responses to systemic yohimbine.

Banihashemi L, Rinaman L (2006) Noradrenergic inputs to the bed nucleus of the stria terminalis and paraventricular nucleus of the hypothalamus underlie hypothalamic-pituitary-adrenal axis but not hypophagic or conditioned avoidance responses to systemic yohimbine. J Neurosci 26(44):11442-11453. doi: 10.1523/JNEUROSCI.3561-06.2006 Summary: Yohimbine (YO) is an a2 adrenoceptor antagonist that increases transmitter release from adrenergic/noradrenergic (NA) neurons.

Noradrenergic inputs to the bed nucleus of the stria terminalis and paraventricular nucleus of the hypothalamus underlie hypothalamic-pituitary-adrenal axis but not hypophagic or conditioned avoidance responses to systemic yohimbine. Read More »

Basal forebrain and saporin cholinergic lesions: the devil dwells in delivery details.

Kalinchuk AV, Porkka-Heiskanen T, McCarley RW (2006) Basal forebrain and saporin cholinergic lesions: the devil dwells in delivery details. Sleep 29:1385-1389. doi: 10.1093/sleep/29.11.1385 Summary: The authors of this commentary discuss results presented by Blanco-Centurion et al. The topic is the role of adenosine in the basal forebrain in the control of sleep homeostasis. Discussion covers

Basal forebrain and saporin cholinergic lesions: the devil dwells in delivery details. Read More »

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