Author name: Kristen Hartman

Roles of the FGF-FGFR signaling system in cancer development and inflammation

Wiedlocha A, Haugsten EM, Zakrzewska M (2021) Roles of the FGF-FGFR signaling system in cancer development and inflammation. Cells 10(9):2231. doi: 10.3390/cells10092231 PMID: 34571880 Objective: To highlight the latest advances in understanding the role of the FGF-FGFR signaling system in the development of neoplastic diseases and in the induction and maintenance of inflammation and its […]

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Tetrahydrocurcumin ameliorates kidney injury and high systolic blood pressure in high-fat diet-induced type 2 diabetic mice

Sangartit W, Ha KB, Lee ES, Kim HM, Kukongviriyapan U, Lee EY, Chung CH (2021) Tetrahydrocurcumin ameliorates kidney injury and high systolic blood pressure in high-fat diet-induced type 2 diabetic mice. Endocrinol Metab (Seoul) 36(4):810-822. doi: 10.3803/EnM.2021.988 PMID: 34474516 Objective: To investigate the protective effect of tetrahydrocurcumin (THU) on intrarenal RAS expression, kidney injury, and

Tetrahydrocurcumin ameliorates kidney injury and high systolic blood pressure in high-fat diet-induced type 2 diabetic mice Read More »

Neuroscience 2021 and Targeting Trends

Targeting Topics /

Have you read Targeting Trends newsletters? Now in a more convenient format, the ATS newsletters are accessible on our website. Features include summaries of the latest publications, FAQ to answer product questions, and articles with cutting edge research shared by featured scientists. Plus cameo appearances by our beloved cats. Flip through the pages of the newsletters like

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Annual ATS Poster of the Year Winners

Meetings Abstracts /

Neuroscience 2019 Truckenbrod LM, Bumanglag AV, Chun E, Hernandez A, Federico QP, Maurer AP, Sloviter RS, Burke SN (2019) Targeted hippocampal GABA neuron ablation produces hippocampal sclerosis, epilepsy, and dissociable effects on the Morris water maze and object-place paired association tasks. Neuroscience 2019 Abstracts 158.03. Society for Neuroscience, Chicago, IL An epileptogenic role for hippocampal

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The effects of orexin-A and orexin receptors on anxiety- and depression-related behaviors in a male rat model of post-traumatic stress disorder

Han D, Shi Y, Han F (2022) The effects of orexin-A and orexin receptors on anxiety- and depression-related behaviors in a male rat model of post-traumatic stress disorder. J Comp Neurol 530(3):592-606. doi: 10.1002/cne.25231 Objective: To determine the role of the orexin system in mediating anxiety- and depression-related behaviors in PTSD. Summary: Intracerebroventricular administration of

The effects of orexin-A and orexin receptors on anxiety- and depression-related behaviors in a male rat model of post-traumatic stress disorder Read More »

Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants

Dookwah M, Wagner SK, Ishihara M, Yu SH, Ulrichs H, Kulik MJ, Zeltner N, Dalton S, Strauss KA, Aoki K, Steet R, Tiemeyer M (2021) Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants. bioRxiv 2021.07.29.454399. doi: 10.1101/2021.07.29.454399 Related Products: NGFr (ME20.4, p75) Mouse Monoclonal (Cat. #AB-N07)

Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants Read More »

How are adenosine and adenosine A2A receptors involved in the pathophysiology of amyotrophic lateral sclerosis?

Mori A, Cross B, Uchida S, Kerrick Walker J, Ristuccia R (2021) How are adenosine and adenosine A2A receptors involved in the pathophysiology of amyotrophic lateral sclerosis?. Biomedicines 9(8):1027. doi: 10.3390/biomedicines9081027 Objective: To examine potential biomarkers and the acute symptomatic pharmacology, including respiratory motor neuron control, of adenosine A2A receptor antagonism, and to explore the

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Pain and depression comorbidity causes asymmetric plasticity in the locus coeruleus neurons

Llorca-Torralba M, Camarena-Delgado C, Suárez-Pereira I, Bravo L, Mariscal P, Garcia-Partida JA, López-Martín C, Wei H, Pertovaara A, Mico JA, Berrocoso E (2022) Pain and depression comorbidity causes asymmetric plasticity in the locus coeruleus neurons. Brain 145(1):154-167. doi: 10.1093/brain/awab239 Summary: There is strong comorbidity between chronic pain and depression. This study explores how this comorbidity

Pain and depression comorbidity causes asymmetric plasticity in the locus coeruleus neurons Read More »

Effects of propofol on sleep architecture and sleep-wake systems in rats

Yue XF, Wang AZ, Hou YP, Fan K (2021) Effects of propofol on sleep architecture and sleep-wake systems in rats. Behav Brain Res 411:113380. doi: 10.1016/j.bbr.2021.113380 Objective: To characterize the effects of propofol on the profile of sleep–wake states and cortical electroencephalogram (EEG) power spectral density in rats following intraperitoneal injection. Summary: The high dose

Effects of propofol on sleep architecture and sleep-wake systems in rats Read More »

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