Author name: Kristen Hartman

Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican.

Bogen O, Dina OA, Gear RW, Levine JD (2009) Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican. Neuroscience 159:780-786. doi: 10.1016/j.neuroscience.2008.12.049 Summary: Monocyte chemoattractant protein 1 (MCP-1) is involved in generation of inflammatory and neuropathic pain, but the mechanisms underlying this involvement are not understood. Rats received 3.2 µg […]

Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican. Read More »

Neurotrophic signaling molecules associated with cholinergic damage in young and aged rats: environmental enrichment as potential therapeutic agent.

Paban V, Chambon C, Manrique C, Touzet C, Alescio-Lautier B (2011) Neurotrophic signaling molecules associated with cholinergic damage in young and aged rats: environmental enrichment as potential therapeutic agent. Neurobiol Aging 32(3):470-485. doi: 10.1016/j.neurobiolaging.2009.03.010 Summary: This study examined the potential of long-term environmental enrichment as a therapeutic agent for cholinergic damage. Rats received bilateral injections

Neurotrophic signaling molecules associated with cholinergic damage in young and aged rats: environmental enrichment as potential therapeutic agent. Read More »

Anti-amnesic properties of (+/-)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats.

Antonini V, Prezzavento O, Coradazzi M, Marrazzo A, Ronsisvalle S, Arena E, Leanza G (2009) Anti-amnesic properties of (+/-)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats. J Neurochem 109:744-754. doi: 10.1111/j.1471-4159.2009.06000.x Summary: Sigma-1 receptors are found throughout the central nervous system, and are thought to be a

Anti-amnesic properties of (+/-)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats. Read More »

Cognitive performances of cholinergically depleted rats following chronic donepezil administration.

Cutuli D, Foti F, Mandolesi L, De Bartolo P, Gelfo F, Federico F, Petrosini L (2009) Cognitive performances of cholinergically depleted rats following chronic donepezil administration. J Alzheimers Dis 17(1):161-176. doi: 10.3233/JAD-2009-1040 PMID: 19221411 Summary: The authors examined whether donepezil could improve cognitive functions in rats with lesions of the cholinergic cells in the forebrain.

Cognitive performances of cholinergically depleted rats following chronic donepezil administration. Read More »

Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain.

Rivat C, Vera-Portocarrero LP, Ibrahim MM, Mata HP, Stagg NJ, De Felice M, Porreca F, Malan TP (2009) Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain. Eur J Neurosci 29:727-737. doi: 10.1111/j.1460-9568.2009.06616.x Summary: Opioids activate hyperalgesia and allodynia. The authors test the hypothesis that NK-1

Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain. Read More »

Developmental forebrain cholinergic lesion and environmental enrichment: behaviour, CA1 cytoarchitecture and neurogenesis.

Frechette M, Rennie K, Pappas BA (2009) Developmental forebrain cholinergic lesion and environmental enrichment: behaviour, CA1 cytoarchitecture and neurogenesis. Brain Res 1252:172-182. doi: 10.1016/j.brainres.2008.11.082 Summary: The authors investigated the effect of neonatal cholinergic lesions on plasticity in the presence or absence of enrichment. Each lateral ventricle of 7 day-old rats received 300 ng of 192-IgG-SAP

Developmental forebrain cholinergic lesion and environmental enrichment: behaviour, CA1 cytoarchitecture and neurogenesis. Read More »

Neuroprotective effects of testosterone on the morphology and function of somatic motoneurons following the death of neighboring motoneurons.

Little CM, Coons KD, Sengelaub DR (2009) Neuroprotective effects of testosterone on the morphology and function of somatic motoneurons following the death of neighboring motoneurons. J Comp Neurol 512:359-372. doi: 10.1002/cne.21885 Summary: Atrophy of androgen-sensitive motoneurons due to proximity to damaged motoneurons can be attenuated by testosterone. This work examined whether typical motoneurons respond in

Neuroprotective effects of testosterone on the morphology and function of somatic motoneurons following the death of neighboring motoneurons. Read More »

Effects of the selective lesions of cholinergic septohippocampal neurons on different forms of memory and learning process.

Dashniani MG, Beseliia GV, Maglakelidze GA, Burdzhanadze MA, Chkhikvishvili N (2009) Effects of the selective lesions of cholinergic septohippocampal neurons on different forms of memory and learning process. Georgian Med News 166:81-85. Summary: The hippocampus is crucial for the ability to recollect everyday events and factual knowledge. Here the authors looked at the role of

Effects of the selective lesions of cholinergic septohippocampal neurons on different forms of memory and learning process. Read More »

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