Author name: Kristen Hartman

GLP-1 attenuates intestinal fat absorption and chylomicron production via vagal afferent nerves originating in the portal vein

Hoffman S, Alvares D, Adeli K (2022) GLP-1 attenuates intestinal fat absorption and chylomicron production via vagal afferent nerves originating in the portal vein. Mol Metab 65:101590. doi: 10.1016/j.molmet.2022.101590 PMID: 36067913 Objective: To examine the effect of vagal GLP-1 signaling on intestinal fat absorption and lipoprotein production. Summary: Selective deafferentation of GLP-1R-containing nodose neurons with […]

GLP-1 attenuates intestinal fat absorption and chylomicron production via vagal afferent nerves originating in the portal vein Read More »

Norepinephrine innervation of the supraoptic nucleus contributes to increased copeptin and dilutional hyponatremia in male rats

Aikins AO, Little JT, Rybalchenko N, Cunningham JT (2022) Norepinephrine innervation of the supraoptic nucleus contributes to increased copeptin and dilutional hyponatremia in male rats. Am J Physiol Regul Integr Comp Physiol 323(5):R797-R809. doi: 10.1152/ajpregu.00086.2022 PMID: 36189988 Objective: Authors hypothesized that the A1/A2 noradrenergic neurons support chronic release of arginine vasopressin in cirrhosis leading to

Norepinephrine innervation of the supraoptic nucleus contributes to increased copeptin and dilutional hyponatremia in male rats Read More »

CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells

Kim S, Shukla RK, Yu H, Baek A, Cressman SG, Golconda S, Lee GE, Choi H, Reneau JC, Wang Z, Huang CA, Liyanage NPM, Kim S (2022) CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells. Front Immunol 13:1011190. doi: 10.3389/fimmu.2022.1011190 Objective: To use a new murine testing model

CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells Read More »

A role for thalamic projection GABAergic neurons in circadian responses to light

Brock O, Gelegen CE, Sully P, Salgarella I, Jager P, Menage L, Mehta I, Jęczmień-Łazur J, Djama D, Strother L, Coculla A, Vernon A, Brickley S, Holland P, Cooke S, Delogu A (2022) A role for thalamic projection GABAergic neurons in circadian responses to light. J Neurosci 42(49):9158-9179. doi: 10.1523/JNEUROSCI.0112-21.2022 PMID: 36280260 Related Products: Melanopsin

A role for thalamic projection GABAergic neurons in circadian responses to light Read More »

ZAP Antibody Internalization Kit Introduction

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ZAP Antibody Internalization Kit Also available in French | German | Japanese | Korean | Mandarin | Italian | Portuguese | Spanish ZAP Antibody Internalization Kit Explainer Whiteboard Browse kit options and order your kit. keywords: research, drug development, bind to cell types, ZAP Antibody Internalization Kit, screen antibodies, binding, internalization, cytotoxicity assay, specific, secondary, saporin, primary, cell surface marker, internalized

ZAP Antibody Internalization Kit Introduction Read More »

The role of macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer

Gudgeon J, Marin-Rubio JL, Trost M (2022) The role of macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer. Front Immunol 13:1012002. doi: 10.3389/fimmu.2022.1012002 PMID: 36325338 Objective: Review the role of Macrophage scavenger receptor 1 (MSR1) in health and disease, focusing on the molecular mechanisms influencing expression, its effect on disease process, macrophage function

The role of macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer Read More »

Aerobic exercise training reduces atherogenesis induced by low-sodium diet in LDL receptor knockout mice

Bochi APG, Ferreira GDS, Del Bianco V, Pinto PR, Rodrigues LG, Trevisani MDS, Furukawa LNS, Bispo KCS, da Silva AA, Velosa APP, Nakandakare ER, Machado UF, Teodoro WPR, Passarelli M, Catanozi S (2022) Aerobic exercise training reduces atherogenesis induced by low-sodium diet in LDL receptor knockout mice. Antioxidants (Basel) 11(10):2023. doi: 10.3390/antiox11102023 PMID: 36290746 Objective:

Aerobic exercise training reduces atherogenesis induced by low-sodium diet in LDL receptor knockout mice Read More »

Uncovering central and peripheral pain mechanisms in Alzheimer’s disease

Silva AR (2022) Uncovering central and peripheral pain mechanisms in Alzheimer’s disease. King’s College London Thesis. Objective: To investigate alterations within the nociceptive pathways, under neuropathic pain conditions. Summary: The data suggest a disrupted opioidergic tone in TASTPM mice, which followed by peripheral nerve injury, is mediated by peripheral immune cells. Related Products: Anti-DBH-SAP (Cat.

Uncovering central and peripheral pain mechanisms in Alzheimer’s disease Read More »

Analysis of the sequence preference of saporin by deep sequencing

Hauf S, Rotrattanadumrong R, Yokobayashi Y (2022) Analysis of the sequence preference of saporin by deep sequencing. ACS Chem Biol 17(9):2619-2630. doi: 10.1021/acschembio.3c00733 PMID: 35969718 Objective: To study sequence-specific depurination of oligo nucleotides caused by saporin. Summary: Data shows the sequence preference of saporin for different substrates and show that the GAGA motif is not

Analysis of the sequence preference of saporin by deep sequencing Read More »

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