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Aerobic exercise training reduces atherogenesis induced by low-sodium diet in LDL receptor knockout mice

Bochi APG, Ferreira GDS, Del Bianco V, Pinto PR, Rodrigues LG, Trevisani MDS, Furukawa LNS, Bispo KCS, da Silva AA, Velosa APP, Nakandakare ER, Machado UF, Teodoro WPR, Passarelli M, Catanozi S (2022) Aerobic exercise training reduces atherogenesis induced by low-sodium diet in LDL receptor knockout mice. Antioxidants (Basel) 11(10):2023. doi: 10.3390/antiox11102023 PMID: 36290746

Objective: To investigate the efficacy of aerobic exercise training (AET) in the prevention of dyslipidemia, insulin resistance (IR), and atherogenesis induced by severe low-sodium (LS) diet.

Summary: AET counteracts the deleterious effects of chronic LS diet in atherogenesis by reducing peripheral insulin resistance, lipid infiltration, carboxymethyllysine, receptor for advanced glycation end products, 4-HNE, and AT1 receptor in the intima-media of the brachiocephalic trunk in LDL receptor knockout mice.

Usage: IF staining (1:50)

Related Products: Angiotensin II receptor (AT-1R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N27AP)

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