Author name: Kristen Hartman

Medial septal cholinergic neurons are necessary for context-place memory but not episodic-like memory.

Easton A, Fitchett AE, Eacott MJ, Baxter MG (2011) Medial septal cholinergic neurons are necessary for context-place memory but not episodic-like memory. Hippocampus 21(9):1021-1027. doi: 10.1002/hipo.20814 Summary: Although it is clear that neurodegenerative diseases cause memory impairment, it is uncertain to what extent cholinergic deficits cause this loss of function. The authors administered a total […]

Medial septal cholinergic neurons are necessary for context-place memory but not episodic-like memory. Read More »

Gene expression profile in rat hippocampus with and without memory deficit.

Paban V, Farioli F, Romier B, Chambon C, Alescio-Lautier B (2010) Gene expression profile in rat hippocampus with and without memory deficit. Neurobiol Learn Mem 94(1):42-56. doi: 10.1016/j.nlm.2010.03.005 Summary: This work examined a wide range of gene expression in the rat hippocampus after bilateral injections of 192-IgG-SAP (Cat. #IT-01) – 37.5 ng per side in

Gene expression profile in rat hippocampus with and without memory deficit. Read More »

Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: Effects on proactive interference.

Pang KCH, Jiao X, Sinha S, Beck KD, Servatius RJ (2011) Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: Effects on proactive interference. Hippocampus 21(8):835-846. doi: 10.1002/hipo.20799 Summary: Recent work implicates the medial septum (MS) and diagonal band (DB) in the control of proactive interference —

Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: Effects on proactive interference. Read More »

Pain is a salient “stressor” that is mediated by corticotropin-releasing factor-1 receptors.

Hummel M, Cummons T, Lu P, Mark L, Harrison JE, Kennedy JD, Whiteside GT (2010) Pain is a salient “stressor” that is mediated by corticotropin-releasing factor-1 receptors. Neuropharmacology 59(3):160-166. doi: 10.1016/j.neuropharm.2010.05.001 Summary: Given that corticotrophin-releasing factor (CRF) plays a major role in the response to stress, the authors investigated the role CRF-1 receptors may play

Pain is a salient “stressor” that is mediated by corticotropin-releasing factor-1 receptors. Read More »

Hindbrain catecholamine neurons modulate the growth hormone but not the feeding response to ghrelin.

Emanuel AJ, Ritter S (2010) Hindbrain catecholamine neurons modulate the growth hormone but not the feeding response to ghrelin. Endocrinology 151(7):3237-3246. doi: 10.1210/en.2010-0219 Summary: In this work the authors investigated the role of hindbrain catecholamine neurons in the response to a gastrointestinal peptide, ghrelin. Rats received 42 ng injections of anti-DBH-SAP (Cat. #IT-03) into the

Hindbrain catecholamine neurons modulate the growth hormone but not the feeding response to ghrelin. Read More »

Induction of CD4(+)CD25(+) T regulatory cells with CD103 depletion.

Zikri NN, Schumer E, Wang JJ, Gaughan A, Hadley GA, Moffatt-Bruce SD (2010) Induction of CD4(+)CD25(+) T regulatory cells with CD103 depletion. J Surg Res 163(1):162-168. doi: 10.1016/j.jss.2010.04.021 Summary: CD8+ T cells expressing CD103 have been shown to play a key role in the rejection of renal allografts. Use of M290-SAP (a custom saporin conjugation)

Induction of CD4(+)CD25(+) T regulatory cells with CD103 depletion. Read More »

Selective lesion of the developing central noradrenergic system: Short- and long-term effects and reinnervation by noradrenergic-rich tissue grafts.

Coradazzi M, Gulino R, Garozzo S, Leanza G (2010) Selective lesion of the developing central noradrenergic system: Short- and long-term effects and reinnervation by noradrenergic-rich tissue grafts. J Neurochem 114(3):761-771. doi: 10.1111/j.1471-4159.2010.06800.x Summary: The authors removed noradrenergic neurons in the locus coeruleus/subcoeruleus complex of neonatal rats with 0.25-1.0 µg bilateral injections of anti-DBH-SAP (Cat. #IT-03).

Selective lesion of the developing central noradrenergic system: Short- and long-term effects and reinnervation by noradrenergic-rich tissue grafts. Read More »

Postnatal development and functional adaptations of the melanopsin photoreceptive system in the albino mouse retina.

Gonzalez-Menendez I, Contreras F, Cernuda-Cernuda R, Provencio I, Garcia-Fernandez JM (2010) Postnatal development and functional adaptations of the melanopsin photoreceptive system in the albino mouse retina. Invest Ophthalmol Vis Sci 51(9):4840-4847. doi: 10.1167/iovs.10-5253 PMID: 20435589 Summary: Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) adjust the circadian pacemaker of mammals by detecting light. The authors tracked

Postnatal development and functional adaptations of the melanopsin photoreceptive system in the albino mouse retina. Read More »

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