Author name: Kristen Hartman

SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas.

Mitra N, Banda K, Altheide TK, Schaffer L, Johnson-Pais TL, Beuten J, Leach RJ, Angata T, Varki N, Varki A (2011) SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas. J Biol Chem 286(26):23003-23011. doi: 10.1074/jbc.M111.244152 Summary: Siglec 12 (sialic acid-binding immunoglobulin-like lectin 12) is a sugar molecule that has mutated […]

SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas. Read More »

Brain and serum levels of nerve growth factor in a rat model of Alzheimer’s disease

Gelfo F, Tirassa P, De Bartolo P, Caltagirone C, Petrosini L, Angelucci F (2011) Brain and serum levels of nerve growth factor in a rat model of Alzheimer’s disease. J Alzheimers Dis 25(2):213-217. doi: 10.3233/JAD-2011-110047 PMID: 21368378 Objective: Using nerve growth factor (NGF) as a marker of disease progression in Alzheimer’s disease using cholinergic depletion

Brain and serum levels of nerve growth factor in a rat model of Alzheimer’s disease Read More »

A common substrate for prefrontal and hippocampal inhibition of the neuroendocrine stress response.

Radley JJ, Sawchenko PE (2011) A common substrate for prefrontal and hippocampal inhibition of the neuroendocrine stress response. J Neurosci 31(26):9683-95. doi: 10.1523/JNEUROSCI.6040-10.2011 Summary: In order to better understand how response to emotional stress is regulated, the authors injected 114 ng of GAT-1-SAP (Cat. #IT-32) into each side of the anterior bed nucleus of the

A common substrate for prefrontal and hippocampal inhibition of the neuroendocrine stress response. Read More »

Enhanced control of attention by stimulating mesolimbic-corticopetal cholinergic circuitry.

St Peters M, Demeter E, Lustig C, Bruno JP, Sarter M (2011) Enhanced control of attention by stimulating mesolimbic-corticopetal cholinergic circuitry. J Neurosci 31(26):9760-9771. doi: 10.1523/JNEUROSCI.1902-11.2011 Summary: Motivation and attention interact to preserve cognitive performance under challenging conditions. In order to better define the circuitry connecting these two processes, the authors lesioned the prefrontal cortex

Enhanced control of attention by stimulating mesolimbic-corticopetal cholinergic circuitry. Read More »

Neural and hormonal control of food hoarding.

Bartness TJ, Keen-Rhinehart E, Dailey MJ, Teubner BJ (2011) Neural and hormonal control of food hoarding. Am J Physiol Regul Integr Comp Physiol 301(3):R641-R655. doi: 10.1152/ajpregu.00137.2011 Summary: Hoarding of food is a commonly found behavior in humans and animals. This review discusses the neuronal and hormonal processes involved in the control of food hoarding. Several

Neural and hormonal control of food hoarding. Read More »

BDNF concentrations are decreased in serum and parietal cortex in immunotoxin 192 IgG-Saporin rat model of cholinergic degeneration.

Angelucci F, Gelfo F, De Bartolo P, Caltagirone C, Petrosini L (2011) BDNF concentrations are decreased in serum and parietal cortex in immunotoxin 192 IgG-Saporin rat model of cholinergic degeneration. Neurochem Int 59(1):1-4. doi: 10.1016/j.neuint.2011.04.010 Summary: Brain-derived neurotrophic factor (BDNF) plays a role in neuronal function during the degeneration of neurons caused by pathological conditions

BDNF concentrations are decreased in serum and parietal cortex in immunotoxin 192 IgG-Saporin rat model of cholinergic degeneration. Read More »

Brain stem catecholamines circuitry: Activation by alcohol and role in the hypothalamic-pituitary-adrenal response to this drug.

Lee S, Craddock Z, Rivier C (2011) Brain stem catecholamines circuitry: Activation by alcohol and role in the hypothalamic-pituitary-adrenal response to this drug. J Neuroendocrinol 23(6):531-541. doi: 10.1111/j.1365-2826.2011.02131.x Summary: In this work the authors investigated mechanisms underlying the stimulatory effect of alcohol on the hypothalamic-pituitary-adrenal axis (HPA). One method used was 33-ng injections of anti-DBH-SAP

Brain stem catecholamines circuitry: Activation by alcohol and role in the hypothalamic-pituitary-adrenal response to this drug. Read More »

Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters.

I’anson H, Jethwa PH, Warner A, Ebling FJ (2011) Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters. Physiol Behav 103(3-4):268-278. doi: 10.1016/j.physbeh.2011.02.035 Summary: The role of central histaminergic mechanisms on seasonal catabolic state was investigated in hamsters. Siberian hamsters received bilateral 3.8-ng injections of orexin-SAP (Cat. #IT-20) into the tuberomammillary posterior hypothalamic region. Saporin

Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters. Read More »

Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity.

King T, Qu C, Okun A, Mercado R, Ren J, Brion T, Lai J, Porreca F (2011) Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity. Pain 152(9):1997-2005. doi: 10.1016/j.pain.2011.04.020 Summary: Whether exaggerated pain response to a normally innocuous tactile stimulus should be defined as allodynia has been debated. Through the use

Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity. Read More »

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