Author name: Kristen Hartman

Medial septal cholinergic neurotransmission is essential for social memory in mice

Shivakumar AB, Mehak SF, Gupta A, Gangadharan G (2025) Medial septal cholinergic neurotransmission is essential for social memory in mice. Prog Neuropsychopharmacol Biol Psychiatry 136:111207. doi: 10.1016/j.pnpbp.2024.111207 PMID: 39615870 Objective: To identify the physiological link between medial septal dependent cholinergic theta oscillations in the hippocampus and social memory behavior. Summary: Selective ablation of cholinergic neurons […]

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Dopamine release and dopamine-related gene expression in the amygdala are modulated by the gastrin-releasing peptide in opposite directions during stress-enhanced fear learning and extinction

Morishata Y, Fuentes I, Gonzalez-Salinas S, Favate J, Mejaes J, Zushida K, Nishi A, Hevi C, Goldsmith N, Buyske S, Sillivan SE, Miller CA, Kandel ER, Uchida S, Shah P, Alarcon JM, Barker DJ, Shumyatsky GP (2025) Dopamine release and dopamine-related gene expression in the amygdala are modulated by the gastrin-releasing peptide in opposite directions

Dopamine release and dopamine-related gene expression in the amygdala are modulated by the gastrin-releasing peptide in opposite directions during stress-enhanced fear learning and extinction Read More »

NGFR Products

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The p75 neurotrophin receptor (p75NTR), also known as the low affinity nerve growth factor receptor, binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. It is a 75kDa membrane-spanning glycoprotein lacking intrinsic tyrosine kinase activity. p75 is expressed in various parts of the brain, notably in the basal forebrain by cholinergic

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NGFR Antibody Videos

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NGFR Antibody Videos An introduction to NGFR Antibodies. What are they and how can you use them? More languages available More languages available keywords: P75NTR, NGFR, Alzheimer’s Disease, dementia, basal forebrain, animal model, neuronal loss, low affinity nerve growth factor, neurotrophin receptors, mesenchyme, Anti-NGFR, Anti-Nerve Growth Factor, 192-IgG, p75, brain, neuroscience

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Phase-separating peptide coacervates with programmable material properties for universal intracellular delivery of macromolecules

Sun Y, Wu X, Li J, Radiom M, Mezzenga R, Verma CS, Yu J, Miserez A (2024) Phase-separating peptide coacervates with programmable material properties for universal intracellular delivery of macromolecules. Nat Commun 15(1):10094. doi: 10.1038/s41467-024-54463-z PMID: 39572548 Objective: To systematically manipulate the sequence of Phase-separating peptides (PSPs) to unravel the relationships between their molecular structure,

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Fos expression in A1/C1 neurons of rats exposed to hypoxia, hypercapnia, or hypercapnic hypoxia

Kato K, Serizawa R, Yokoyama T, Nakamuta N, Yamamoto Y (2024) Fos expression in A1/C1 neurons of rats exposed to hypoxia, hypercapnia, or hypercapnic hypoxia. Neurosci Lett 843:138024. doi: 10.1016/j.neulet.2024.138024 PMID: 39442648 Objective: To compare the distribution of Fos expression in catecholaminergic neurons with immunoreactivity for dopamine-β-hydroxylase (DBH) of the ventrolateral medulla exposed to hypoxia

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Improved safety of chimeric antigen receptor T cells indirectly targeting antigens via switchable adapters

Park HB, Kim KH, Kim JH, Kim SI, Oh YM, Kang M, Lee S, Hwang S, Lee H, Lee T, Park S, Lee JE, Jeong GR, Lee DH, Youn H, Choi EY, Son WC, Chung SJ, Chung J, Choi K (2024) Improved safety of chimeric antigen receptor T cells indirectly targeting antigens via switchable adapters.

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Investigating the role of the ventral anterior cingulate cortex (vacc) in placebo analgesia

Rehal SK (2024) Investigating the role of the ventral anterior cingulate cortex (vacc) in placebo analgesia. Univ Toronto Thesis. Objective: To examine whether opioid receptors in the ventral anterior cingulate cortex (vACC) were critical for the placebo response evoked by conditioning with 10 mg/kg morphine. Summary: Significant differences were observed before and after injection of

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Involvement of peptidergic Edinger-Westphal nucleus in the neurobiology of migraine and acute alcohol exposure

Ammar AO (2024) Involvement of peptidergic Edinger-Westphal nucleus in the neurobiology of migraine and acute alcohol exposure. Univ Pecs Thesis. Objective: To confirm the role of Edinger-Westphal nucleus/urocortin1 (EWcp/UCN1) neurons in migraine. They hypothesized that selective ablation of EWcp/UCN1 neurons will influence the migraine-related behaviors induced by CGRP. Summary: Upon selective ablation of EWcp/UCN1 neurons,

Involvement of peptidergic Edinger-Westphal nucleus in the neurobiology of migraine and acute alcohol exposure Read More »

Spinal pain processing in arthritis: Neuron and glia (inter)actions

Schaible HG, König C, Ebersberger A (2024) Spinal pain processing in arthritis: Neuron and glia (inter)actions. J Neurochem 168(11):3644-3662. doi: 10.1111/jnc.15742 PMID: 36520021 Objective: To address the mechanisms of spinal sensitization evoked by arthritis. Summary: Neutralization of spinal cytokines by intrathecal interventions attenuates mechanical hyperalgesia. This effect may in part result from local suppression of

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