Zlatkovic J (2025) Gravitostat: A homeostatic regulator of body weight. Univ of Gothenburg Thesis.
Objective: To focus on elucidating central and peripheral physiological mechanisms behind load-induced body weight reduction.
Summary: The main findings in this thesis include the identification of a group of neurons activated by increased load in the medial Nucleus of Solitary Tract (mNTS) and the dorsal horn (DH) of the Lumbar Spine (LS) in mice.
Usage: Stereotaxic brain delivery of neurotoxin saporin conjugated with anti-dopamine-B-hydroxylase antibodies (5 ng, Anti-DBH-SAP, IT-03) was used as a method of targeted ablation of noradrenergic (NE) neurons in the Nucleus of the Solitary Tract in the brainstem.
Related Products: Anti-DBH-SAP (Cat. #IT-03)