Author name: Kristen Hartman

Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin.

Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes D, Tate T, Czechowicz A, Kfoury Y, Ruchika F, Rossi D, Verdine G, Mansour M, Scadden D (2016) Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Nat Biotechnol 34:738-745. doi: 10.1038/nbt.3584 Summary: To demonstrate correction of a clinically relevant disease, we employed […]

Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Read More »

Neuroprotective effects of fermented soybean products (Cheonggukjang) manufactured by mixed culture of Bacillus subtilis MC31 and Lactobacillus sakei 383 on trimethyltin-induced cognitive defects mice

Go J, Kim JE, Kwak MH, Koh EK, Song SH, Sung JE, Kim DS, Hong JT, Hwang DY (2016) Neuroprotective effects of fermented soybean products (Cheonggukjang) manufactured by mixed culture of Bacillus subtilis MC31 and Lactobacillus sakei 383 on trimethyltin-induced cognitive defects mice. Nutr Neurosci 19(6):247-259. doi: 10.1179/1476830515Y.0000000025 PMID: 25923962 Objective: This study aimed to

Neuroprotective effects of fermented soybean products (Cheonggukjang) manufactured by mixed culture of Bacillus subtilis MC31 and Lactobacillus sakei 383 on trimethyltin-induced cognitive defects mice Read More »

Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves.

Jiao J, Xiong W, Wang L, Yang J, Qiu P, Hirai H, Shao L, Milewicz D, Chen Y, Yang B (2016) Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves. EBioMedicine 10:282-290. doi: 10.1016/j.ebiom.2016.06.045 PMID: 27394642 Summary: Individuals with bicuspid aortic valves (BAV) are at a higher

Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves. Read More »

Featured Article: Targeted depletion of hematopoietic stem cells promises safer transplantation

Palchaudhuri R (2016) Featured Article: Targeted depletion of hematopoietic stem cells promises safer transplantation. Targeting Trends 17(3) Related Products: Streptavidin-ZAP (Cat. #IT-27) Read the featured article in Targeting Trends. See Also: Palchaudhuri R et al. Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Nat Biotechnol 34:738-745, 2016. Skulimowska I et al.

Featured Article: Targeted depletion of hematopoietic stem cells promises safer transplantation Read More »

Retinal waves modulate an intraretinal circuit of intrinsically photosensitive retinal ganglion cells.

Arroyo D, Kirkby L, Feller M (2016) Retinal waves modulate an intraretinal circuit of intrinsically photosensitive retinal ganglion cells. J Neurosci 36:6892-6905. doi: 10.1523/JNEUROSCI.0572-16.2016 PMID: 27358448 Summary: The researchers explore the neural circuits underlying the ipRGC driven light responses of the developing retina and the mechanisms by which retinal waves regulate these circuits. They demonstrate

Retinal waves modulate an intraretinal circuit of intrinsically photosensitive retinal ganglion cells. Read More »

Bone morphogenetic protein 4 promotes craniofacial neural crest induction from human pluripotent stem cells.

Mimura S, Suga M, Okada K, Kinehara M, Nikawa H, Furue M (2016) Bone morphogenetic protein 4 promotes craniofacial neural crest induction from human pluripotent stem cells. Int J Dev Biol 60:21-28. doi: 10.1387/ijdb.160040mk PMID: 26934293 Usage: Immunocytochemistry and flow cytometry Related Products: NGFr (ME20.4, p75) Mouse Monoclonal (Cat. #AB-N07)

Bone morphogenetic protein 4 promotes craniofacial neural crest induction from human pluripotent stem cells. Read More »

Possible involvement of the rat hypothalamo-neurohypophysial/-spinal oxytocinergic pathways in acute nociceptive responses.

Matsuura T, Kawasaki M, Hashimoto H, Yoshimura M, Motojima Y, Saito R, Ueno H, Maruyama T, Ishikura T, Sabanai K, Mori T, Ohnishi H, Onaka T, Sakai A, Ueta Y (2016) Possible involvement of the rat hypothalamo-neurohypophysial/-spinal oxytocinergic pathways in acute nociceptive responses. J Neuroendocrinol 28(6) doi: 10.1111/jne.12396 Summary: It has been suggested that the

Possible involvement of the rat hypothalamo-neurohypophysial/-spinal oxytocinergic pathways in acute nociceptive responses. Read More »

The p75 neurotrophin receptor augments survival signaling in the striatum of pre-symptomatic Q175(WT/HD) mice.

Wehner A, Milen A, Albin R, Pierchala B (2016) The p75 neurotrophin receptor augments survival signaling in the striatum of pre-symptomatic Q175(WT/HD) mice. Neuroscience 324:297-306. doi: 10.1016/j.neuroscience.2016.02.069 PMID: 26947127 Summary: Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder. It’s characterized by a combination of motor, cognitive, and psychiatric features. Striatal spiny neurons are dependent

The p75 neurotrophin receptor augments survival signaling in the striatum of pre-symptomatic Q175(WT/HD) mice. Read More »

Locus coeruleus noradrenergic innervation of the amygdala facilitates alerting-induced constriction of the rat tail artery.

Mohammed M, Kulasekara K, Ootsuka Y, Blessing W (2016) Locus coeruleus noradrenergic innervation of the amygdala facilitates alerting-induced constriction of the rat tail artery. Am J Physiol Regul Integr Comp Physiol 310:R1109-1119. doi: 10.1152/ajpregu.00058.2016 Summary: The researchers tested the hypothesis that release of noradrenaline within the amygdala is important for the occurrence of SCVARS (sympathetic

Locus coeruleus noradrenergic innervation of the amygdala facilitates alerting-induced constriction of the rat tail artery. Read More »

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