Author name: Kristen Hartman

Saporin Publication highlighting 192-IgG-SAP and Anti-DBH-SAP

Targeting Topics /

Summary: These results indicate a prominent role of NA-neurons vs. ACh ones in impairments of working memory, relevant for Alzheimer’s Disease. Usage: Bilateral icv injection of 192-IgG-SAP and/or Anti-DBH-SAP. G. Leanza and R. Zorec. Function 2023, 4(1) DOI: 10.1093/function/zqac060.  We would be pleased to send you our 2023 ATS calendar. Click here to provide us your […]

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Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats

Iqbal Z, Lei Z, Ramkrishnan AS, Liu S, Hasan M, Akter M, Lam YY, Li Y (2023) Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats. Commun Biol 6:10. doi: 10.1038/s42003-022-04405-6 PMID: 36604595 Objective: To identify the role of norepinephrine in colorectal distention (sub-threshold for acute pain) induced conditioned

Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats Read More »

Towards astroglia-based noradrenergic hypothesis of Alzheimer’s disease

Leanza G, Zorec R (2023) Towards astroglia-based noradrenergic hypothesis of Alzheimer’s disease. Function (Oxf) 4(1):zqac060., IT. doi: 10.1093/function/zqac060 PMID: 36590326 Summary: These results indicate a prominent role of NA-neurons vs. ACh neurons in impairments of working memory, relevant for AD, and are consistent with an astrocyte-specific metabolic impairment in a mouse model of intellectual disability.

Towards astroglia-based noradrenergic hypothesis of Alzheimer’s disease Read More »

The impact of advanced age on morphine anti-hyperalgesia and the role of mu opioid receptor signaling in the periaqueductal gray of male and female rats

Fullerton E (2022) The impact of advanced age on morphine anti-hyperalgesia and the role of mu opioid receptor signaling in the periaqueductal gray of male and female rats. Georgia State University doi: 10.57709/30509896 Objective: To investigate the impact of advanced age on the antihyperalgesic effect of morphine, as well as its association with changes in

The impact of advanced age on morphine anti-hyperalgesia and the role of mu opioid receptor signaling in the periaqueductal gray of male and female rats Read More »

Pituitary adenylate cylase-activating polypeptide receptor: Multiple signaling pathways involved in energy homeostasis

Maunze B (2022) Pituitary adenylate cylase-activating polypeptide receptor: Multiple signaling pathways involved in energy homeostasis. Marquette University Dissertations 1212. Thesis. Objective: To determine the endogenous role of pituitary adenylate cyclase activating polypeptide (PACAP) in affecting the ventromedial nuclei (VMN) of the hypothalamus and its control of feeding and energy expenditure through the Type I PAC1

Pituitary adenylate cylase-activating polypeptide receptor: Multiple signaling pathways involved in energy homeostasis Read More »

CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells

Kim S, Shukla RK, Yu H, Baek A, Cressman SG, Golconda S, Lee GE, Choi H, Reneau JC, Wang Z, Huang CA, Liyanage NPM, Kim S (2022) CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells. Front Immunol 13:1011190. doi: 10.3389/fimmu.2022.1011190 Objective: To use a new murine testing model

CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells Read More »

A role for thalamic projection GABAergic neurons in circadian responses to light

Brock O, Gelegen CE, Sully P, Salgarella I, Jager P, Menage L, Mehta I, Jęczmień-Łazur J, Djama D, Strother L, Coculla A, Vernon A, Brickley S, Holland P, Cooke S, Delogu A (2022) A role for thalamic projection GABAergic neurons in circadian responses to light. J Neurosci doi: 10.1523/JNEUROSCI.0112-21.2022 PMID: 36280260 Related Products: Melanopsin Rabbit

A role for thalamic projection GABAergic neurons in circadian responses to light Read More »

ZAP Antibody Internalization Kit Introduction

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ZAP Antibody Internalization Kit Also available in French | German | Japanese | Korean | Mandarin | Italian | Portuguese | Spanish ZAP Antibody Internalization Kit Explainer Whiteboard Browse kit options and order your kit. keywords: research, drug development, bind to cell types, ZAP Antibody Internalization Kit, screen antibodies, binding, internalization, cytotoxicity assay, specific, secondary, saporin, primary, cell surface marker, internalized

ZAP Antibody Internalization Kit Introduction Read More »

The role of macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer

Gudgeon J, Marin-Rubio JL, Trost M (2022) The role of macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer. Front Immunol 13:1012002. doi: 10.3389/fimmu.2022.1012002 Objective: Review the role of Macrophage scavenger receptor 1 (MSR1) in health and disease, focusing on the molecular mechanisms influencing expression, its effect on disease process, macrophage function and signaling

The role of macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer Read More »

Aerobic exercise training reduces atherogenesis induced by low-sodium diet in LDL receptor knockout mice

Bochi APG, Ferreira GDS, Del Bianco V, Pinto PR, Rodrigues LG, Trevisani MDS, Furukawa LNS, Bispo KCS, da Silva AA, Velosa APP, Nakandakare ER, Machado UF, Teodoro WPR, Passarelli M, Catanozi S (2022) Aerobic exercise training reduces atherogenesis induced by low-sodium diet in LDL receptor knockout mice. Antioxidants (Basel) 11(10):2023. doi: 10.3390/antiox11102023 PMID: 36290746 Objective:

Aerobic exercise training reduces atherogenesis induced by low-sodium diet in LDL receptor knockout mice Read More »

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