16q1

Targeting Trends Newsletter 16q1

Below are links to view the quarterly newsletter Targeting Trends. You can also download the full PDF here. If you would like to be added to the mailing list, please complete the information on our contact page. Dermorphin-SAP is highlighted this quarter in the cover article “Striatal patch compartment lesions reduce cocaine-induced repetitive behaviors” by by …

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Targeting Tools: Brand New Website

We are proud to announce the release of our newly redesigned website. It has been crafted to reflect content our customers access most often and to provide new visitors an easier way to learn about ATS’s products and services. Immediately you will notice streamlined menus, simple navigation and access to the information you need, any …

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Targeting Tools: Beta Products

In an effort to accelerate offering new targeted toxins to our customers, we launched the Beta Product program early in 2015. Publications and collaborations are an invaluable source of independent data to support the efficacy of our products. To help streamline this process, we’ve created a catalog of new targeted toxins that we’re offering to …

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Targeting Talk: Safety of the Toxin

Q: Our QA group wants to know about the safety of the toxin in your conjugates? What precautions should we take in handling saporin products? A: Saporin is a Type 1 ribosome-inactivating protein (RIP), due to its N-glycosidase activity, from the seeds of Saponaria officinalis. It was first described by Fiorenzo Stirpe and his colleagues …

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Targeting Topics 16q1

Endogenous opioid activity in the anterior cingulate cortex is required for relief of pain. Navratilova E, Xie JY, Meske D, Qu C, Morimura K, Okun A, Arakawa N, Ossipov M, Fields HL, Porreca F. J Neurosci 35(18):7264-7271, 2015. There are a number of neuronal circuits involved in the processing of pain, including those that control …

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Cover Article: Striatal patch compartment lesions reduce cocaine-induced repetitive behaviors

by Kristen Ashley Horner and collaborators R. Murray and M.C. LoganMercer University School of Medicine, Savannah, GA 31404 Repeated exposure to psychostimulants, such as cocaine, can result in patterns of repetitive, inflexible behaviors, known as stereotypy.[1,2] These inflexible behaviors are thought to be similar to the type of behaviors observed with certain psychiatric disorders, such …

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