Below are links to view the quarterly newsletter Targeting Trends. If you would like to be added to the mailing list, please complete the information on our contact page. Newsletter Highlights Spring Brain Conference 25th Anniversary (page 2) Targeting Talk: Antibody questions…answered (page 5) ZAP Antibody Internalization Kit (page 7) Complete and Submit the Targeting Teaser …
Screening large numbers of antibodies for the ability to internalize can be prohibitively expensive in both cost and time. The ZAP Antibody Internalization Kit contains all the components needed for three 96-well plates, or 288 tests. The ability to perform a diagnostic screen that is amenable to high-throughput methods, prior to direct conjugation of those …
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Does AB-T183 (Lauric Acid Rat Polyclonal, Conjugated) recognize lauric acid alone, or does it need to be conjugated to something (a protein carrier)? This antibody targets conjugated Lauric Acid. It does not recognize free lauric acid. Antisera was preabsorbed on protein carriers and ammonium sulfate-purified. Using a conjugate Lauric acid-Gluteraldehyde-Protein Carrier (PC), antibody specificity was …
We have a publication in review and put this statement in the paper, “The mouse monoclonal antibody to the low affinity nerve growth factor receptor (p75NTR; Advanced Targeting Systems) was derived from immunization of mice with WM245 melanoma cells and recognizes p75NTR in human, primate, rabbit, sheep, dog, cat, and pig. According to the manufacturer’s …
Neurotrophic factors rescue basal forebrain cholinergic neurons and improve performance on a spatial learning test. Lee YS, Danandeh A, Baratta J, Lin CY, Yu J, Robertson RT. Exp Neurol 249C:178-186, 2013. It is thought that therapeutic treatments of the cholinergic system may be a viable treatment for Alzheimer’s disease. In order to examine this hypothesis …
Contributed by Francesco Ferrini (1) and Yves De Koninck (2,3) 1) Department of Veterinary Sciences, University of Turin,10095 Grugliasco, Turin, Italy 2) Institut universitaire en santé mentale de Québec, QC, G1J 2G3, Canada 3) Department of Psychiatry and Neuroscience, Université Laval, Québec, QC, G13 7P4, Canada Morphine-induced hyperalgesia and tolerance dramatically limit the use of …