13q2

Targeting Trends 2013 Newsletter

2013, issue 1: Role of cholinergic neurons in the nucleus accumbens and their involvement in schizophrenic pathology / by F LaPlante / featuring Anti-ChAT-SAP (Cat. #IT-42), Rabbit IgG-SAP (Cat. #IT-35) SFN Poster of the Year Targeting Tools: Anti-ChAT-SAP (Cat.#IT-42) 2013, issue 2: Antibodies to glycosphingolipids: An attractive tool for targeted delivery of cytotoxic agents to tumor …

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Targeting Tools: FabFc-ZAP – A new secondary conjugate

Background of General Preparation and Components: Over the last few years, riding on the coattails of the established customer base for the ZAP line of secondary conjugates, Fab-ZAP has become the most popular ATS product group in the catalog. Combining species-specific monovalent secondary antibodies with the cytotoxic ribosome-inactivating protein, Saporin, the Fab-ZAP line of products …

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Targeting Talk: Targeting B Cells

How can I target B-cells? Which secondary conjugate should I use? ATS makes secondary conjugates that use your primary antibody to target cells for elimination. Just mix your primary antibody with a secondary antibody conjugated to the ribosome-inactivating protein, Saporin, to screen your antibodies. The cells targeted by your primary antibody are eliminated. Hum-ZAP (Cat. …

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Targeting Topics 13q2

Direct Retino-Raphe Projection Alters Serotonergic Tone and Affective Behavior. Ren C, Luan L, Wui-Man Lau B, Huang X, Yang J, Zhou Y, Wu X, Gao J, Pickard GE, So KF, Pu M. Neuropsychopharmacology Epub 2013. Although recent work has shown that some intrinsically photosensitive retinal ganglion cells (ipRGCs) are responsible for processing nonimage-forming visual functions, …

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Cover Article: Antibodies to glycosphingolipids: An attractive tool for targeted delivery of cytotoxic agents to tumor cells

Contributed by Jose Luis Daniotti, Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC, UNC-CONICET), Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina. Glycosphingolipids (GSLs) are amphipathic molecules consisting of a ceramide lipid moiety linked to a glycan chain of variable length and structure. Among these are found the …

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