07q3 – Advanced Targeting Systems

Targeting Trends 2007 Newsletter

Read the 2007 Newsletters and recent scientific references 2007, issue 1: Cholinergic Immunolesioning Produced Tangle-like Inclusions in TgCRND8 Brain / by Chauhan N / featuring mu p75-SAP (Cat. #IT-16) SFN Poster of the Year Targeting Talk: Targeted Toxin Controls Targeting Tools Anti-Pseudomonas aeurginosa (Cat. #AB-T057) Anti-Conjugated Glutathione (Cat. #AB-T01) Anti-Conjugated Acetylcholine (Cat. #AB-T02) Anti-Conjugated Dopamine (Cat. #AB-T11) […]

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New Targets: The Claustrum

News Tools / Kristen Hartman

What is the claustrum? The simple answer is that it’s a brain structure that lies under the insular and piriform cortices. What it does is rather unclear, but one hypothesis has drawn considerable attention. The claustrum contains projections to the entire cortex, and this may indicate that it plays an important role in brain function.

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Targeting Tools: Targeting B-Cell Leukemias and Lymphomas

News Tools / Kristen Hartman

Anti-CD22 (UV22-2) Mouse Monoclonal This IgG1k antibody (Cat. #AB-36) recognizes the group A epitope of the human B-cell antigen, CD22. Clone UV22-2 reacts exclusively with cells of human B-cell lineage. The fluorescent conjugate mouse IgG-FITC (Cat. #FL-07) is available as a research tool to use with this and other mouse monoclonal antibodies. Anti-CD22-SAP Immunotoxin This

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Targeted Therapy for Chronic Pain

SP SAP Drug Development / Kristen Hartman

In 1997, SP-SAP (a chemical conjugate of Substance P and the ribosome-inactivating protein saporin) was created to eliminate Substance P receptor (SPR) neurons that propagate the signal for chronic pain. ATS has successfully completed preclinical studies, safety tests in animal models and a GLP toxicology study in rat, funded both internally and by the National

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