Read the 2004 Newsletters 2004, issue 1: Cholinergic Deafferentation of the Entorhinal Cortex Impairs Working Memory for Novel, but not Familiar Stimuli in a Delayed Non-Match to Sample (DNMS) Task / by McGaughy J / featuring 192-IgG-SAP (Cat. #IT-01) ATS Gets New Facility for SP-SAP Production SFN Poster of the Year Targeting Talk: Not the …
Advanced Targeting Systems is pleased to announce the availability of polyclonal antibodies to somatostatin receptor (SSTr) sub-types 1 and 4. SSTr1 antiserum, Cat. #AB-N19 SSTr1 affinity-purified, Cat. #AB-N20AP SSTr4 affinity-purified, Cat. #AB-N21AP Antibody to SSTr1 SSTr1 is a 391 amino acid G-protein-coupled receptor that contains three glycosylation sites and that is expressed in several areas …
Targeting Tools: Somatostatin Receptor Targeting Read More »
Does the release of acetylcholine in septal slices originate from intrinsic cholinergic neurons bearing p75(NTR) receptors? A study using 192 IgG-saporin lesions in rats. Birthelmer A, Lazaris A, Riegert C, Marques Pereira P, Koenig J, Jeltsch H, Jackisch R, Cassel JC. Neuroscience 122(4):1059-1071, 2003. The authors used 0.8 µg injections of 192-Saporin (Cat. #IT-01) into …
Progress continues to be made in moving SP-SAP closer to clinical trials as a treatment for chronic pain. The latest development is the leasing of a 3700-sq ft facility adjacent to the current ATS facility in San Diego. This facility will be converted to GMP (Good Manufacturing Practice) space suitable for production of SP-SAP for …
Contributed by ATS’s 2003 Society for Neuroscience Poster of the Year Award Winner:Dr. Jill McGaughy, Boston University, 64 Cummington St., Boston, MA 02215 Muscarinic cholinergic receptor activation in entorhinal cortex (EC) activates intrinsic depolarizing membrane currents, which cause self-sustained spiking activity in single neurons.[1] This effect may underlie delay activity and match-dependent activity changes in …