Somatostatin Receptor-3 is one of five receptor subtypes termed SSTR1-5. They are G-protein-coupled receptors characterized by seven transmembrane domains with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon, and growth hormone, as well as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Somatostatin receptors are activated via somatostatin secretion in nerve and endocrine cells.
This peptide corresponds to a sequence from the extracellular domain of Somatostatin Receptor-3 (SSTR3). 100 micrograms of the peptide is diluted into 500 microliters of PBS containing 100 micrograms BSA.
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