Anti-ChAT-SAP [IT-42]

a tool for eliminating cells that express choline acetyltransferase in multiple species; targeted via the affinity-purified rabbit polyclonal antibody to ChAT, eliminated via saporin

SKU: IT-42 Category: Product Size: 25 ug, 100 ug, 250 ug, 1 mg | Antibody Type: affinity-purified, Polyclonal | Host: Rabbit | Reactivity: guinea pig, Human, Mouse, pig, rabbit, rat | Conjugate: saporin | Usage: eliminates cells |

Choline acetyltransferase (ChAT) catalyzes the synthesis of the neurotransmitter acetylcholine (ACh) from choline and acetyl-CoA in cholinergic neurons. ChAT serves as a specific marker for cholinergic neurons in both peripheral and central nervous systems. Dysfunction of cholinergic neurons underlies aspects of clinical symptoms found in neurological and psychiatric disorders such as Alzheimer’s disease, Down and Rett syndromes.

Anti-ChAT-SAP specifically eliminates cells that express choline acetyltransferase.

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