antibodies

601 entries

NADPH oxidase contributes to angiotensin II signaling in the nucleus tractus solitarius.

Wang G, Anrather J, Huang J, Speth RC, Pickel VM, Iadecola C (2004) NADPH oxidase contributes to angiotensin II signaling in the nucleus tractus solitarius. J Neurosci 24(24):5516-5524. doi: 10.1523/JNEUROSCI.1176-04.2004 PMID: 15201324

Objective: To investigated whether NADPH oxidase is involved in angiotensin II signaling in central autonomic neurons.

Summary: Angiotensin II (AngII), acting through angiotensin type 1 (AT1 ) receptors, exerts powerful effects on central autonomic networks regulating cardiovascular homeostasis and fluid balanceColocalization of AT-1r’s and a NADPH oxidase subunit provides evidence that NADPH oxidase is involved in the effects of angiotensin II on autonomic neurons.

Usage: Immunolabeling (1:200)

Related Products: Angiotensin II receptor (AT-1AR) Rabbit Polyclonal, affinity-purified (Cat. #AB-N25AP), Angiotensin II receptor (AT-1R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N27AP), Angiotensin II receptor (AT-2R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N28AP)

Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation.

Anton PM, Gay J, Mykoniatis A, Pan A, O’Brien M, Brown D, Karalis K, Pothoulakis C (2004) Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation. Proc Natl Acad Sci U S A 101(22):8503-8508. doi: 10.1073/pnas.0402693101 PMID: 15159534

Related Products: Corticotropin Releasing Hormone Rabbit Polyclonal (Cat. #AB-02)

Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis

Pehar M, Cassina P, Vargas MR, Castellanos R, Viera L, Beckman JS, Estévez AG, Barbeito L (2004) Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem 89(2):464-473. doi: 10.1111/j.1471-4159.2004.02357.x PMID: 15056289

Summary: The role of p75-mediated activity evaluated with p75NTR blocking antibody. Motor neuron loss induced by reactive astrocytes was prevented by blocking the p75NTR.

Related Products: NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01)

Medullary serotonergic neurons and adjacent neurons that express neurokinin-1 receptors are both involved in chemoreception in vivo.

Nattie EE, Li A, Richerson GB, Lappi DA (2004) Medullary serotonergic neurons and adjacent neurons that express neurokinin-1 receptors are both involved in chemoreception in vivo. J Physiol 556(1):235-253. doi: 10.1113/jphysiol.2003.059766 PMID: 14724193

Summary: The retrotrapezoid nucleus contains neurokinin-1 receptor (NK-1r)-expressing neurons that are involved in chemoreception. NK-1r-expressing neurons are also present in areas that contain medullary serotonergic neurons. These serotonergic neurons have been shown to be chemosensitive in vitro. With two 100-nl injections of 1 µM SP-SAP (Cat. #IT-07), anti-SERT-SAP (Cat. #IT-23), or both, the authors examined whether both cell populations are involved in chemoreception in vivo in rats. The results support that separate populations of serotonergic and NK-1r-expressing neurons are each involved in chemoreception in vivo.

Related Products: SP-SAP (Cat. #IT-07), Anti-SERT-SAP (Cat. #IT-23), Antibody to Serotonin Transporter (SERT, Cat. #AB-N09)

Evidence for nitric oxide involvement in experimental autoimmune encephalomyelitis and adjuvant-induced arthritis in Lewis rat.

Mnaimneh S, Damaj M, Barhoumi R, Mouneimne Y, Geffard M, Veyret B, Vincendeau P (2004) Evidence for nitric oxide involvement in experimental autoimmune encephalomyelitis and adjuvant-induced arthritis in Lewis rat. The Pain Clinic 16(3):229-243. doi: 10.1163/1568569041798407 PMID: 0

Related Products: NO-L-Cysteine Mouse Monoclonal, Conjugated (Cat. #AB-T125)

ATM protein overexpression in prostate tumors: possible role in telomere maintenance.

Angele S, Falconer A, Foster CS, Taniere P, Eeles RA, Hall J (2004) ATM protein overexpression in prostate tumors: possible role in telomere maintenance. Am J Clin Pathol 121(2):231-236. doi: 10.1309/JTKG-GGKU-RFX3-XMGT PMID: 14983937

Related Products: TRF1 Mouse Monoclonal (Cat. #AB-37)

Angiotensin II subtype 1A (AT1A) receptors in the rat sensory vagal complex: Subcellular localization and association with endogenous angiotensin.

Huang J, Hara Y, Anrather J, Speth RC, Iadecola C, Pickel VM (2003) Angiotensin II subtype 1A (AT1A) receptors in the rat sensory vagal complex: Subcellular localization and association with endogenous angiotensin. Neuroscience 122(1):21-36. doi: 10.1016/s0306-4522(03)00606-7 PMID: 14596846

Objective: To determine interactive sites in the sensory vagal complex of rat brain using dual immunolabeling of antisera recognizing the AT1-AR and Ang II.

Summary: In the rat sensory vagal complex, AT-1A receptors are strategically positioned for involvement in modulation of the postsynaptic excitability and intracrine hormone-like effects of Ang II. In addition, these receptors have distributions consistent with diverse roles in regulation of transmitter release, regional blood flow and/or vascular permeability.

Usage: Immunolabeling (1:200)

Related Products: Angiotensin II receptor (AT-1AR) Rabbit Polyclonal, affinity-purified (Cat. #AB-N25AP), Angiotensin II receptor (AT-1R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N27AP), Angiotensin II receptor (AT-2R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N28AP)

Ontogeny of the pre-Bötzinger complex in perinatal rats.

Pagliardini S, Ren J, Greer JJ (2003) Ontogeny of the pre-Bötzinger complex in perinatal rats. J Neurosci 23(29):9575-9584. doi: 10.1523/JNEUROSCI.23-29-09575.2003 PMID: 14573537

Related Products: Antibody to NK-1 Receptor (Cat. #AB-N04)

S-nitrosating nitric oxide donors induce long-lasting inhibition of contraction in isolated arteries.

Alencar JL, Lobysheva I, Chalupsky K, Geffard M, Nepveu F, Stoclet JC, Muller B (2003) S-nitrosating nitric oxide donors induce long-lasting inhibition of contraction in isolated arteries. J Pharmacol Exp Ther 307(1):152-159. doi: 10.1124/jpet.103.052605 PMID: 12954813

Related Products: NO-L-Cysteine Mouse Monoclonal, Conjugated (Cat. #AB-T125)

Somatostatin receptors.

Moller LN, Stidsen CE, Hartmann B, Holst JJ (2003) Somatostatin receptors. Biochim Biophys Acta 1616(1):1-84. doi: 10.1016/s0005-2736(03)00235-9 PMID: 14507421

Related Products: Somatostatin Receptor-1 (SSTR1) Mouse Monoclonal (Cat. #AB-N35), Somatostatin Receptor-1 (SSTR1) Rabbit Polyclonal (Cat. #AB-N20), Somatostatin Receptor-5 (SSTR5) Mouse Monoclonal (Cat. #AB-N24)

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