Olfaction, cholinergic basal forebrain degeneration, and cognition in early Parkinson disease

Barrett MJ, Murphy JM, Zhang J, Blair JC, Flanigan JL, Nawaz H, Dalrymple WA, Sperling SA, Patrie J, Druzgal TJ (2021) Olfaction, cholinergic basal forebrain degeneration, and cognition in early Parkinson disease. Parkinsonism Relat Disord 90:27-32. doi: 10.1016/j.parkreldis.2021.07.024

Summary: This study examined the relationship between olfaction, longitudinal change in cholinergic basal forebrain nuclei and their target regions, and cognition in early Parkinson’s Disease.

See: Linster C et al. Selective Loss of Cholinergic Neurons Projecting to the Olfactory System Increases Perceptual Generalization Between Similar, but Not Dissimilar, Odorants. Behav Neurosci 115(4):826-833, 2001.

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