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2021 Targeting Trends Review

Aqueous extract of Solanum nigrum attenuates Angiotensin-II induced cardiac hypertrophy and improves cardiac function by repressing protein kinase C-ζ to restore HSF2 deSUMOlyation and Mel-18-IGF-IIR signaling suppression

Lin HJ, Mahendran R, Huang HY, Chiu PL, Chang YM, Day CH, Chen RJ, Padma VV, Liang-Yo Y, Kuo WW,...

Nonsteroidal anti-inflammatory drug (ketoprofen) delivery differentially impacts phrenic long-term facilitation in rats with motor neuron death induced by intrapleural CTB-SAP injections

Borkowski LF, Keilholz AN, Smith CL, Canda KA, Nichols NL (2021) Nonsteroidal anti-inflammatory drug (ketoprofen) delivery differentially impacts phrenic long-term...

The role of BDNF-mediated neuroplasticity in cardiovascular regulation within the hypothalamus and brainstem

Thorsdottir DJ (2021) The role of BDNF-mediated neuroplasticity in cardiovascular regulation within the hypothalamus and brainstem. Univ Vermont, Dept Pharmacology...

The molecular basis for IL-31 production and IL-31-mediated itch transmission: from biology to drug development

Kunimura K, Fukui Y (2021) The molecular basis for IL-31 production and IL-31-mediated itch transmission: from biology to drug development....

Effects of age on sexually dimorphic food protection behavior associated with hippocampal cholinergic deafferentation.

Osterlund Oltmanns JR, Schaeffer EA, Blackwell AA, Pietrucha SA, Yang H, Tasi S, Kartje GL, Wallace D (2021) Effects of...

Nociception impedes grasping recovery in the spinal cord injured rat.

Walker J, Kim T, Giszter S, Detloff MR (2021) Nociception impedes grasping recovery in the spinal cord injured rat. Neuroscience...

A brief history of saporin and its contributions to neuroscience

Shramm PA, Ancheta LR, Bouajram R, Lappi DA (2021) A brief history of saporin and its contributions to neuroscience. Neuroscience...

Contribution of small diameter non-peptidergic primary afferent neurons to central neuropathic pain in a new, more clinically relevant mouse model of multiple sclerosis

Nguyen KL, Lamerand SR. Deshpande RP, Taylor BK (2021) Contribution of small diameter non-peptidergic primary afferent neurons to central neuropathic...

The role of the patch compartment of striatum in reward-driven behaviors

Ahn J, Christy DJ, Horner K (2021) The role of the patch compartment of striatum in reward-driven behaviors. Neuroscience 2021...

A neuropeptide code for itch

Chen ZF (2021) A neuropeptide code for itch. Nat Rev Neurosci 22(12):758-776. doi: 10.1038/s41583-021-00526-9 Related Products: Bombesin-SAP (Cat. #IT-40)

Role of microglia and astrocytes in spinal cord injury induced neuropathic pain

Miranpuri GS, Bali P, Nguyen J, Kim JJ, Modgil S, Mehra P, Buttar S, Brown G, Yutuc N, Singh H,...

Evaluation of the activity of choline acetyltransferase from different synaptosomal fractions at the distinct stages of spatial learning in the morris water maze

Storozheva ZI, Zakharova EI, Proshin AT (2021) Evaluation of the activity of choline acetyltransferase from different synaptosomal fractions at the...

Engrafted stem cell therapy for Alzheimer’s disease: A promising treatment strategy with clinical outcome

Salwa, Kumar L (2021) Engrafted stem cell therapy for Alzheimer’s disease: A promising treatment strategy with clinical outcome. J Control...

Learning of food preferences: mechanisms and implications for obesity & metabolic diseases

Berthoud HR, Morrison CD, Ackroff K, Sclafani A (2021) Learning of food preferences: mechanisms and implications for obesity & metabolic...

Expert Opinion: Managing sleep disturbances in people with epilepsy

Nobili L, Beniczky S, Eriksson SH, Romigi A, Ryvlin P, Toledo M, Rosenzweig I (2021) Expert Opinion: Managing sleep disturbances...

Heart failure impairs mood and memory in male rats and down-regulates the expression of numerous genes important for synaptic plasticity in related brain regions

Parent MB, Ferreira-Neto HC, Kruemmel AR, Althammer F, Patel AA, Keo S, Whitley KE, Cox DN, Stern JE (2021) Heart...

Overexpression of nerve growth factor in the hippocampus induces behavioral changes in rats with 192IgG-saporin-induced cholinergic deficit

Dobryakova YV, Zaichenko MI, Spivak YS, Stepanichev MY, Markevich VA, Bolshakov AP (2021) Overexpression of nerve growth factor in the...

The protective effects of AT2R agonist, CGP42112A, against angiotensin ii-induced oxidative stress and inflammatory response in astrocytes: role of AT2R/PP2A/NFκB/ROS signaling

Bhat SA, Fatima Z, Sood A, Shukla R, Hanif K (2021) The protective effects of AT2R agonist, CGP42112A, against angiotensin...

The biology of hematopoietic stem cells and its clinical implications

Skulimowska I, Sosniak J, Gonka M, Szade A, Jozkowicz A, Szade K (2021) The biology of hematopoietic stem cells and...

Neural circuitry underlying REM sleep: A review of the literature and current concepts

Wang YQ, Liu WY, Li L, Qu WM, Huang ZL (2021) Neural circuitry underlying REM sleep: A review of the...