Gonzalez EA, Leitão SAT, Dos Santos Soares D, Tavares AMV, Giugliani R, Baldo G, Matte U (2021) Cardiac pathology in Mucopolysaccharidosis I mice: Losartan modifies ERK1/2 activation during cardiac remodeling. J Inherit Metab Dis 44(3):740-750. doi: 10.1002/jimd.12327 PMID: 33145772
Objective: To investigate whether the pathways influenced by losartan and propranolol may modulate the cardiac remodeling process in MPS I mice.
Summary: Losartan and propranolol restore the heart function and could be used to ameliorate the cardiac disease in MPS I.
Usage: Western Blot 1:400
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