Di Sebastiano AR, Yong-Yow S, Wagner L, Lehman MN, Coolen LM (2010) Orexin mediates initiation of sexual behavior in sexually naive male rats, but is not critical for sexual performance. Horm Behav 58(3):397-404. doi: 10.1016/j.yhbeh.2010.06.004
Summary: In this work the role of endogenous orexin-A and B in male sexual behavior was investigated. Rats received a total of 400 ng of orexin-SAP (Cat. #IT-20) into the hypothalamus in each hemisphere. Blank-SAP (Cat. #IT-21) was used as a control. The lesions facilitated initiation of sexual behavior in naïve males, and reduced anxiety-like behaviors. The data suggest that orexin may play a role in arousal and anxiety related to sexual behavior in naïve animals, but is not critical for performance or motivation.
Related Products: Orexin-B-SAP (Cat. #IT-20), Blank-SAP (Cat. #IT-21)