Zhong F, Liu L, Wei J-L, Hu Z-L, Li L, Wang S, Xu J-M, Zhou X-F, Li C-Q, Yang Z-Y, Dai R-P (2019) Brain-derived neurotrophic factor precursor in the hippocampus regulates both depressive and anxiety-like behaviors in rats. Front Psychiatry 9:776. doi: 10.3389/fpsyt.2018.00776 PMID: 30740068 Objective: To investigate the role of proBDNF in the hippocampus […]
Pinto LG, Souza GR, Kusuda R, Lopes AH, Sant’Anna MB, Cunha FQ, Ferreira SH, Cunha TM (2019) Non-peptidergic nociceptive neurons are essential for mechanical inflammatory hypersensitivity in mice. Mol Neurobiol 56(8):5715-5728. doi: 10.1007/s12035-019-1494-5 Objective: To determine the role of non-peptidergic nociceptors in mediating mechanical inflammatory hypersensitivity in mice. Summary: rIB4-SAP oblates non-peptidergic neurons as displayed
Abadir E, Bryant C, Larsen S, Clark GJ (2019) Targeting the niche: Depleting haemopoietic stem cells with targeted therapy. Bone Marrow Transplant 54:961–968. doi: 10.1038/s41409-019-0445-0 Summary: Anti-mouse CD45 ADC (clone 104-Saporin) Depletes mature lymphoid cells and HSPC, conditioning allows for high level sustained multilineage engraftment of congenic mice. Anti-mouse ADC (CD117-saporin) Combined with T cell
Targeting the niche: Depleting haemopoietic stem cells with targeted therapy. Read More »
Ortgies DH, García-Villalón ÁL, Granado M, Amor S, Rodríguez EM, Santos HDA, Yao J, Rubio-Retama J, Jaque D (2019) Infrared fluorescence imaging of infarcted hearts with Ag2S nanodots. Nano Res 12:749–757. doi: 10.1007/s12274-019-2280-4 PMID: 0 Objective: To investigate the potential application of functionalized Ag2S nanodots for accurate imaging of damaged myocardium tissues after a myocardial
Infrared fluorescence imaging of infarcted hearts with Ag2S nanodots. Read More »
Plum T (2019) Identification of lineage-specific markers for therapeutic targeting of mast cells. Ruperto-Carola University of Heidelberg, Germany Thesis. doi: 10.11588/heidok.00023555 Usage: Mice were injected i.v. with either 100 µg of 1:1 molar mixture of biotinylated CD63 antibody and Streptavidin-ZAP (60 µg mAb + 40 µg SAP) or with 40 µg SAP alone. All injections
Identification of lineage-specific markers for therapeutic targeting of mast cells. Read More »
Xu H, Chen L, Zhang X, Jiang X, Tian W, Yu W, Wang X, Tian J, Su D (2019) Central cholinergic neuronal degeneration promotes the development of postoperative cognitive dysfunction. Lab Invest 99(7):1078-1088. doi: 10.1038/s41374-018-0174-9 Usage: 1 microliter of mu-p75-SAP at a concentration of 0.8 μg/μl was injected into the lateral ventricles. Related Products: mu
Cat. #IT-69 Nppb-SAP Meng, Qing-Tao and Liu, Xian-Yu and Liu, Xue-Ting and Barry, Devin M. and Jin, Hua and Yang, Qianyi and Sun, Yu and Wan, Li and Jin, Jin-Hua and Munanairi, Admire and Kim, Ray and Yin, Jun and Tao, Ailin and Chen, Zhou-Feng, Cross-Talk between Distinct Receptors Shapes Itch Behavior in the Spinal
News from Science: Nppb in Itch / CRH antibody cross-reactivity Read More »
Chew C, Kiley B, Sengelaub D (2019) Neuroprotective effects on the morphology of somatic motoneurons following the death of neighboring motoneurons: A role for microglia. Dev Neurobiol 79:131-154. doi: 10.1002/dneu.22652 Related Products: CTB-SAP (Cat. #IT-14)
Seven YB, Mitchell GS (2019) Mechanisms of compensatory plasticity for respiratory motor neuron death. Respir Physiol Neurobiol 265:32-39. doi: 10.1016/j.resp.2019.01.001 Summary: Discusses recent advances in understanding of mechanisms giving rise to compensatory respiratory plasticity in response to respiratory motor neuron death. Related Products: CTB-SAP (Cat. #IT-14)
Mechanisms of compensatory plasticity for respiratory motor neuron death. Read More »
Koshy Cherian A, Kucinski A, Wu R, deJong IEM, Sarter M (2019) Co-treatment with rivastigmine and idalopirdine reduces the propensity for falls in a rat model of falls in Parkinson’s disease. Psychopharmacology 236:1701–1715. doi: 10.1007/s00213-018-5150-y Objective: The authors used a longer and more taxing rotating beam apparatus to determine the potential therapeutic efficacy of idalopirdine