Author name: Kristen Hartman

The role of the brain in the regulation of peripheral noradrenaline-producing organs in rats during morphogenesis.

Murtazina AR, Nikishina YO, Dil’mukhametova LK, Sapronova AY, Ugrumov MV (2019) The role of the brain in the regulation of peripheral noradrenaline-producing organs in rats during morphogenesis. Dokl Biochem Biophys 486(1):243-246. doi: 10.1134/S1607672919030207 Related Products: Anti-DBH-SAP (Cat. #IT-03)

The role of the brain in the regulation of peripheral noradrenaline-producing organs in rats during morphogenesis. Read More »

RGS14414 treatment induces memory enhancement and rescues episodic memory deficits.

Masmudi‐Martin M, Navarro‐Lobato I, López‐Aranda MF, Delgado G, Martín‐Montañez E, Quiros‐Ortega ME, Carretero‐Rey M, Narváez L, Garcia‐Garrido MF, Posadas S, López‐Téllez JF, Blanco E, Jiménez‐Recuerda I, Granados‐Durán P, Paez‐Rueda J, López JC and Khan ZU (2019) RGS14414 treatment induces memory enhancement and rescues episodic memory deficits. FASEB J 33:11804-11820. doi: 10.1096/fj.201900429RR Objective: To investigate the

RGS14414 treatment induces memory enhancement and rescues episodic memory deficits. Read More »

Neuroprotective Effects of Exercise

Neuroprotective Effects of Exercise on the Morphology of Somatic Motoneurons Following the Death of Neighboring Motoneurons. (2019). Chew C, & Sengelaub DR. Neurorehabil Neural Repair, epub ahead of print 1545968319860485.  IT-14:  CTB-SAP Objective:  To explore whether exercise shows the same neuroprotective effect on induced dendritic atrophy as that seen with androgen treatment.Summary:  Exercise following neural

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Latest Itch research using Targeted Toxins

Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch. (2019). Cell Reports, 28 (3):625-639.e626. Acton D, Ren X, Di Costanzo S, Dalet A, Bourane S, Bertocchi I, Eva C, & Goulding M. Objective:  To determine the central pathway for mechanical itch.Summary:  NPY-Y1 signaling regulates the transmission of innocuous tactile information by establishing biologically relevant thresholds for

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A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours.

Fu R, Han C-F, Ni T, Di L, Liu L-J, Lv W-C, Bi Y-R, Jiang N, He Y, Li H-M, Wang S, Xie H, Chen B-A, Wang X-S, Weiss SJ, Lu T, Guo Q-L, Wu Z-Q (2019) A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours. Nat Commun 10(1):3210. doi: 10.1038/s41467-019-11278-7 PMID: 31324807

A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours. Read More »

Latest Alzheimer’s Disease research using Targeting Tools

3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain. Nizari S, Carare RO, Romero IA, & Hawkes CA. (2019). Front Aging Neurosci, 11 (172).  IT-16: mu p75-SAP Objective:  To further characterize the effect of the loss of cholinergic innervation on the NVU

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Spinal neuropeptide Y1 receptor-expressing neurons form an essential excitatory pathway for mechanical itch.

Acton D, Ren X, DiCostanzo S, Dalet A, Bourane S, Bertocchi I, Eva C, Goulding M (2019) Spinal neuropeptide Y1 receptor-expressing neurons form an essential excitatory pathway for mechanical itch. Cell Reports 28(3):625-639.e6 . doi: 10.1016/j.celrep.2019.06.033 Objective: To determine the central pathway for mechanical itch. Summary: NPY-Y1 signaling regulates the transmission of innocuous tactile information

Spinal neuropeptide Y1 receptor-expressing neurons form an essential excitatory pathway for mechanical itch. Read More »

∆Np63 executes an oncogenic program through the regulation of a common landscape of super-enhancer associated genes in non-small cell lung cancer

Wu SJ, Coarfa C, Abbas H, Checker R, Dhar S, Rajapakshe K, Lee MG, Flores ER (2019) ∆Np63 executes an oncogenic program through the regulation of a common landscape of super-enhancer associated genes in non-small cell lung cancer. Cell Reports 3420369. doi: 10.2139/ssrn.3420369 Objective: To investigate how ΔNp63 serves to maintain lung adenocarcinoma (ADC) and

∆Np63 executes an oncogenic program through the regulation of a common landscape of super-enhancer associated genes in non-small cell lung cancer Read More »

Interleukin-1 reduces food intake and body weight in rat by acting in the arcuate hypothalamus

Chaskiel L, Bristow AD, Bluthé RM, Dantzer R, Blomqvist A, Konsman JP (2019) Interleukin-1 reduces food intake and body weight in rat by acting in the arcuate hypothalamus. Brain Behav Immun 81:560-573. doi: 10.1016/j.bbi.2019.07.017 Summary: The authors tested the hypothesis that IL-1R1 expressing cells in the ARH mediate IL-1β and/or LPS-induced hypophagia in the rat.

Interleukin-1 reduces food intake and body weight in rat by acting in the arcuate hypothalamus Read More »

Light responses of melanopsin-expressing ganglion cells in the foetal mammalian retina

Verweij J, Chaney SY, Bredl D, Vemaraju S, König GM, Kostenis E, Lang RA, Copenhagen DR (2019) Light responses of melanopsin-expressing ganglion cells in the foetal mammalian retina. bioRxiv 675702. doi: 10.1101/675702 Related Products: Melanopsin Rabbit Polyclonal, affinity-purified (Cat. #AB-N39)

Light responses of melanopsin-expressing ganglion cells in the foetal mammalian retina Read More »

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