Author name: Kristen Hartman

A non-genotoxic stem cell therapy boosts lymphopoiesis and averts age-related blood diseases in mice

Konturek-Ciesla A, Zhang Q, Kharazi S, Bryder D (2025) A non-genotoxic stem cell therapy boosts lymphopoiesis and averts age-related blood diseases in mice. Nat Commun 16(1):5129. doi: 10.1038/s41467-025-60464-3 PMID: 40456713 Objective: Application of Hematopoietic stem cell (HSC) transplantation leads to treatment toxicity. Therefore, authors employed a murine transplantation model based on low-intensity conditioning protocols using […]

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Neural mechanisms of context-sensitive behavior in the adult male zebra finch

Anderson KL (2025) Neural mechanisms of context-sensitive behavior in the adult male zebra finch. City Univ NY Thesis. Objective: To test whether oxytocin and dopamine mediate the influence of the social behavior network on the vocal control network in songbirds, enabling context-dependent changes to song. Summary: The study reveals direct anatomical links between hypothalamic nodes

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bTRM control of murine cytomegalovirus cns reactivation

Chauhan P, Hu S, Sheng WS, Prasad S, Lokensgard JR (2025) bTRM control of murine cytomegalovirus cns reactivation. 26(11):5275. doi: 10.3390/ijms26115275 PMID: 40508083 Objective: To determine the role of CD8+ and CD103+ brain-resident memory T cells (bTRMs) in controlling murine cytomegalovirus (MCMV) reactivation in the central nervous system. Summary: Depleting CD103+ bTRMs led to transient

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Reduced neuronal self-avoidance in mouse starburst amacrine cells with only one Pcdhg isoform

McLeod CM, Son S, Haque MN, Garrett AM (2025) Reduced neuronal self-avoidance in mouse starburst amacrine cells with only one Pcdhg isoform. bioRxiv 2025.05.29.656828. doi: 10.1101/2025.05.29.656828 Objective: To determine whether the γC4 isoform of the protocadherin-γ (Pcdhg) gene cluster is sufficient to mediate neuronal self-avoidance in starburst amacrine cells (SACs) in the mouse retina. Summary:

Reduced neuronal self-avoidance in mouse starburst amacrine cells with only one Pcdhg isoform Read More »

Differentiation of brain mural cells from human pluripotent stem cell-derived neural crest by activation of notch3 signaling

Gastfriend BD, Palecek SP, Shusta EV (2025) Differentiation of brain mural cells from human pluripotent stem cell-derived neural crest by activation of notch3 signaling. (eds. Barichello, T.). Blood-Brain Barrier 221:11-35. Humana, New York, NY. doi: 10.1007/978-1-0716-4474-4_2 Objective: To describe a serum-free method to differentiate brain mural cells from human pluripotent stem cells (hPSCs), using lentiviral

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Enteropancreatic neurons drive the glucoregulatory response to ingested lipid

Roberts AG, Meyer L, Norton M, Phuah P, Alonso AM, Dowsett GKC, Cheng S, Dunsterville C, Liu J, Chung PE, Tao Y, Smitherman-Cairns T, Deutsch AB, Chatterjee A, Lam BYH, Hanyaloglu AC, Jones B, Yeo GSH, Salem V, Murphy KG (2025) Enteropancreatic neurons drive the glucoregulatory response to ingested lipid. bioRxiv 2025.05.09.652620. doi: 10.1101/2025.05.09.652620 Objective:

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Magnetic fields influence visual responses in mice

Semo M, Hughes S, Smyllie NJ, Patton AP, Pothecary CA, Tam SKE, Buckland J, Brown LA (2025) Magnetic fields influence visual responses in mice. bioRxiv 2025.05.12.653455. doi: 10.1101/2025.05.12.653455 Objective: To investigate whether magnetic fields influence mammalian retinal function and to determine the role of cryptochromes in mediating this effect. Summary: This study demonstrates that magnetic

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Phrenic motor nucleus astrocytic density and morphology in a rodent model of respiratory motor neuron death

Lewis R, Smith C, Burd E, Nichols N (2025) Phrenic motor nucleus astrocytic density and morphology in a rodent model of respiratory motor neuron death. Am Physiol Soc 40(S1) doi: 10.1152/physiol.2025.40.S1.1115 Objective: Authors hypothesized that astrocytic density would be increased and astrocytic morphology would be altered in the phrenic motor nucleus over the course of

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Do CCKA receptor containing vagal afferent neurons mediate gut-brain inflammatory signals?

Kozlova E, Lam A, Alam S, Shum J, Denys M, Berdasco C, de-Lartigue G, Curras-Collazo M (2025) Do CCKA receptor containing vagal afferent neurons mediate gut-brain inflammatory signals?. Am Physiol Soc 40(S1) doi: 10.1152/physiol.2025.40.S1.2035 Objective: To investigate whether CCKA receptor, containing vagal afferent neurons (VANs), mediate gut-brain inflammatory signaling and contribute to the systemic immune

Do CCKA receptor containing vagal afferent neurons mediate gut-brain inflammatory signals? Read More »

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