Author name: Kristen Hartman

Preferential destruction of cerebellar Purkinje cells by OX7-saporin.

Angner RT, Kelly RM, Wiley RG, Walsh TJ, Reuhl KR (2000) Preferential destruction of cerebellar Purkinje cells by OX7-saporin. Neurotoxicol 21:395-403. Summary: Purkinje cells function as inhibitors and are the sole output of the cerebellar cortex. Angner et al. eliminate these cells in rats with 1-2 µg OX7-SAP (Cat. #IT-02), an immunotoxin that binds the […]

Preferential destruction of cerebellar Purkinje cells by OX7-saporin. Read More »

Immunohistochemical localization of protein 3-nitrotyrosine and S-nitrosocysteine in a murine model of inhaled nitric oxide therapy.

Lorch SA, Foust R 3rd, Gow A, Arkovitz M, Salzman AL, Szabo C, Vayert B, Geffard M, Ischiropoulos H (2000) Immunohistochemical localization of protein 3-nitrotyrosine and S-nitrosocysteine in a murine model of inhaled nitric oxide therapy. Pediatr Res 47(6):798-805. doi: 10.1203/00006450-200006000-00020 PMID: 10832741 Related Products: NO-L-Cysteine Mouse Monoclonal, Conjugated (Cat. #AB-T125)

Immunohistochemical localization of protein 3-nitrotyrosine and S-nitrosocysteine in a murine model of inhaled nitric oxide therapy. Read More »

NGF-mediated alteration of NF-κB binding activity after partial immunolesions to rat cholinergic basal forebrain neurons.

Gu Z, Toliver-Kinsky T, Glasgow J, Werrbach-Perez K, Perez-Polo JR (2000) NGF-mediated alteration of NF-κB binding activity after partial immunolesions to rat cholinergic basal forebrain neurons. Int J Dev Neurosci 18:455-468. doi: 10.1016/s0736-5748(00)00004-6 Summary: After injecting 1.3 µg 192-Saporin (Cat. #IT-01) into the lateral ventricle of rat brain, followed by infusion of NGF antibody, Gu

NGF-mediated alteration of NF-κB binding activity after partial immunolesions to rat cholinergic basal forebrain neurons. Read More »

Cholinergic excitation of septohippocampal GABA but not cholinergic neurons: implications for learning and memory.

Wu M, Shanabrough M, Leranth C, Alreja M (2000) Cholinergic excitation of septohippocampal GABA but not cholinergic neurons: implications for learning and memory. J Neurosci 20(10):3900-3908. doi: 10.1523/JNEUROSCI.20-10-03900.2000 PMID: 10804229 Summary: It has long been assumed that the drug-induced enhancement of learning and memory in both young and aged rats was accomplished through a cholinergic

Cholinergic excitation of septohippocampal GABA but not cholinergic neurons: implications for learning and memory. Read More »

Immunolocalization of the cocaine- and antidepressant-sensitive 1-norepinephrine transporter.

Schroeter S, Apparsundaram S, Wiley RG, Miner LH, Sesack SR, Blakely RD (2000) Immunolocalization of the cocaine- and antidepressant-sensitive 1-norepinephrine transporter. J Comp Neurol 420:211-232. doi: 10.1002/(SICI)1096-9861(20000501)420:23.0.CO;2-3 Summary: Norepinephrine transporters are involved in the response to multiple antidepressants and psychostimulants, but the expression of these proteins has not yet been characterized in the central nervous

Immunolocalization of the cocaine- and antidepressant-sensitive 1-norepinephrine transporter. Read More »

Impaired acquisition of a Morris water maze task following selective destruction of cerebellar Purkinje cells with OX7-saporin.

Gandhi CC, Kelly RM, Wiley RG, Walsh TJ (2000) Impaired acquisition of a Morris water maze task following selective destruction of cerebellar Purkinje cells with OX7-saporin. Behav Brain Res 109:37-47. doi: 10.1016/s0166-4328(99)00160-6 Summary: The cerebellum has been associated with the control of motor activity and voluntary movements. Recent data have shown the cerebellum may also

Impaired acquisition of a Morris water maze task following selective destruction of cerebellar Purkinje cells with OX7-saporin. Read More »

Cholinergic deafferentation of the rabbit cortex: a new animal model of Abeta deposition.

Beach TG, Potter PE, Kuo YM, Emmerling MR, Durham RA, Webster SD, Walker DG, Sue LI, Scott S, Layne KJ, Roher AE (2000) Cholinergic deafferentation of the rabbit cortex: a new animal model of Abeta deposition. Neurosci Lett 283:9-12. doi: 10.1016/s0304-3940(00)00916-2 Related Products: ME20.4-SAP (Cat. #IT-15) Read the featured article in Targeting Trends.

Cholinergic deafferentation of the rabbit cortex: a new animal model of Abeta deposition. Read More »

Recombinant toxins that bind to the urokinase receptor are cytotoxic without requiring binding to the alpha(2)-macroglobulin receptor.

Rajagopal V, Kreitman RJ (2000) Recombinant toxins that bind to the urokinase receptor are cytotoxic without requiring binding to the alpha(2)-macroglobulin receptor. J Biol Chem 275(11):7566-7573. doi: 10.1074/jbc.275.11.7566 Related Products: Saporin (Cat. #PR-01)

Recombinant toxins that bind to the urokinase receptor are cytotoxic without requiring binding to the alpha(2)-macroglobulin receptor. Read More »

Attenuation of the bidirectional effects of chlordiazepoxide and FG 7142 on conditioned response suppression and associated cardiovascular reactivity by loss of cortical cholinergic inputs.

Stowell JR, Berntson GG, Sarter M (2000) Attenuation of the bidirectional effects of chlordiazepoxide and FG 7142 on conditioned response suppression and associated cardiovascular reactivity by loss of cortical cholinergic inputs. Psychopharmacol 150(2):141-149. doi: 10.1007/s002130000443 Summary: The benzodiazepine receptor (BR) is involved in anxiety. It has been hypothesized that cholinergic projections from the CBF are

Attenuation of the bidirectional effects of chlordiazepoxide and FG 7142 on conditioned response suppression and associated cardiovascular reactivity by loss of cortical cholinergic inputs. Read More »

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