Author name: Kristen Hartman

Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants

Dookwah M, Wagner SK, Ishihara M, Yu SH, Ulrichs H, Kulik MJ, Zeltner N, Dalton S, Strauss KA, Aoki K, Steet R, Tiemeyer M (2021) Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants. bioRxiv 2021.07.29.454399. doi: 10.1101/2021.07.29.454399 Related Products: NGFr (ME20.4, p75) Mouse Monoclonal (Cat. #AB-N07)

Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants Read More »

How are adenosine and adenosine A2A receptors involved in the pathophysiology of amyotrophic lateral sclerosis?

Mori A, Cross B, Uchida S, Kerrick Walker J, Ristuccia R (2021) How are adenosine and adenosine A2A receptors involved in the pathophysiology of amyotrophic lateral sclerosis?. Biomedicines 9(8):1027. doi: 10.3390/biomedicines9081027 Objective: To examine potential biomarkers and the acute symptomatic pharmacology, including respiratory motor neuron control, of adenosine A2A receptor antagonism, and to explore the

How are adenosine and adenosine A2A receptors involved in the pathophysiology of amyotrophic lateral sclerosis? Read More »

Pain and depression comorbidity causes asymmetric plasticity in the locus coeruleus neurons

Llorca-Torralba M, Camarena-Delgado C, Suárez-Pereira I, Bravo L, Mariscal P, Garcia-Partida JA, López-Martín C, Wei H, Pertovaara A, Mico JA, Berrocoso E (2022) Pain and depression comorbidity causes asymmetric plasticity in the locus coeruleus neurons. Brain 145(1):154-167. doi: 10.1093/brain/awab239 Summary: There is strong comorbidity between chronic pain and depression. This study explores how this comorbidity

Pain and depression comorbidity causes asymmetric plasticity in the locus coeruleus neurons Read More »

Effects of propofol on sleep architecture and sleep-wake systems in rats

Yue XF, Wang AZ, Hou YP, Fan K (2021) Effects of propofol on sleep architecture and sleep-wake systems in rats. Behav Brain Res 411:113380. doi: 10.1016/j.bbr.2021.113380 Objective: To characterize the effects of propofol on the profile of sleep–wake states and cortical electroencephalogram (EEG) power spectral density in rats following intraperitoneal injection. Summary: The high dose

Effects of propofol on sleep architecture and sleep-wake systems in rats Read More »

TRP channels in cancer pain

de Almeida AS, Bernardes LB, Trevisan G (2021) TRP channels in cancer pain. Eur J Pharmacol 904:174185. doi: 10.1016/j.ejphar.2021.174185 PMID: 34015320 Objective: To describe the role of TRP vanilloid 1 (TRPV1) and TRP ankyrin 1 (TRPA1) involved in cancer pain mechanisms. Summary: Several studies have revealed that the administration of TRPV1 or TRPA1 agonists/antagonists and

TRP channels in cancer pain Read More »

Baoyuan decoction (BYD) attenuates cardiac hypertrophy through ANKRD1-ERK/GATA4 pathway in heart failure after acute myocardial infarction

Meng H, Du Z, Lu W, Wang Q, Sun X, Jiang Y, Wang Y, Li C, Tu P (2021) Baoyuan decoction (BYD) attenuates cardiac hypertrophy through ANKRD1-ERK/GATA4 pathway in heart failure after acute myocardial infarction. Phytomedicine 89:153617. doi: 10.1016/j.phymed.2021.153617 PMID: 34157504 Objective: To explore whether BYD plays a protective role against heart failure (HF) by

Baoyuan decoction (BYD) attenuates cardiac hypertrophy through ANKRD1-ERK/GATA4 pathway in heart failure after acute myocardial infarction Read More »

Centrally projecting edinger-westphal nucleus in the control of sympathetic outflow and energy homeostasis

Cano G, Hernan SL, Sved AF (2021) Centrally projecting edinger-westphal nucleus in the control of sympathetic outflow and energy homeostasis. Brain Sci 11(8):1005. doi: 10.3390/brainsci11081005 Objective: To test the hypothesis that Edinger-Westphal nucleus (EWcp) integrates multimodal signals (stress, thermal, metabolic, endocrine, etc.) and modulates the sympathetic output simultaneously to multiple effector organs to maintain energy

Centrally projecting edinger-westphal nucleus in the control of sympathetic outflow and energy homeostasis Read More »

Injection of anti-proBDNF attenuates hippocampal-dependent learning and memory dysfunction in mice with sepsis-associated encephalopathy

Cui YH, Zhou SF, Liu Y, Wang S, Li F, Dai RP, Hu ZL, Li CQ (2021) Injection of anti-proBDNF attenuates hippocampal-dependent learning and memory dysfunction in mice with sepsis-associated encephalopathy. Front Neurosci 15:665757. doi: 10.3389/fnins.2021.665757 PMID: 34354558 Objective: To study the effects and associated mechanism of hippocampal proBDNF in a lipopolysaccharide (LPS)-induced sepsis-associated encephalopathy

Injection of anti-proBDNF attenuates hippocampal-dependent learning and memory dysfunction in mice with sepsis-associated encephalopathy Read More »

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