Author name: Kristen Hartman

Minocycline in neurodegenerative and psychiatric diseases: An update.

Romero-Miguel D, Lamanna-Rama N, Casquero-Veiga M, Gómez-Rangel V, Desco M, Soto-Montenegro ML (2021) Minocycline in neurodegenerative and psychiatric diseases: An update. Eur J Neurol 28(3):1056-1081. doi: 10.1111/ene.14642 Summary: Review includes the mouse animal model of neurodegenerative disease using mu p75-SAP. Biological Effects: Attenuation of cholinergic neurons loss, glial activation and transcription of pro-inflammatory mediators. Usage: 45 […]

Minocycline in neurodegenerative and psychiatric diseases: An update. Read More »

Intact vagal gut-brain signalling prevents hyperphagia and excessive weight gain in response to high-fat high-sugar diet.

McDougle M, Quinn D, Diepenbroek C, Singh A, de la Serre C, de Lartigue G (2021) Intact vagal gut-brain signalling prevents hyperphagia and excessive weight gain in response to high-fat high-sugar diet. Acta Physiol (Oxf) 231(3):e13530. doi: 10.1111/apha.13530 Objective: To assess the function of the vagus nerve lack specificity. Summary: Intact sensory vagal neurons prevent

Intact vagal gut-brain signalling prevents hyperphagia and excessive weight gain in response to high-fat high-sugar diet. Read More »

Saporin, a polynucleotide-adenosine nucleosidase, may be an efficacious therapeutic agent for SARS-CoV-2 infection

Arslan I, Akgul H, Kara M (2021) Saporin, a polynucleotide-adenosine nucleosidase, may be an efficacious therapeutic agent for SARS-CoV-2 infection. SLAS Discov 26(3):330-335. doi: 10.1177/2472555220970911 Related Products: Saporin (Cat. #PR-01)

Saporin, a polynucleotide-adenosine nucleosidase, may be an efficacious therapeutic agent for SARS-CoV-2 infection Read More »

Activated factor X targeted stored in platelets as an effective gene therapy strategy for both hemophilia A and B

Wang D, Shao X, Wang Q, Pan X, Dai Y, Yao S, Yin T, Wang Z, Zhu J, Xi X, Chen Z, Chen S, Zhang G (2021) Activated factor X targeted stored in platelets as an effective gene therapy strategy for both hemophilia A and B. Clin Transl Med 11(3):e375. doi: 10.1002/ctm2.375 Summary: Treatment of

Activated factor X targeted stored in platelets as an effective gene therapy strategy for both hemophilia A and B Read More »

Tongue and hypoglossal morphology after intralingual cholera toxin B-saporin injection

Lind LA, Lever TE, Nichols NL (2021) Tongue and hypoglossal morphology after intralingual cholera toxin B-saporin injection. Muscle Nerve 63(3):413-420. doi: 10.1002/mus.27131 Objective: To evaluate tongue morphology and ultrastructural changes in hypoglossal neurons and nerve fibers in an inducible rat model of dysphagia. Summary: Preliminary results indicate this model may have translational application to a

Tongue and hypoglossal morphology after intralingual cholera toxin B-saporin injection Read More »

P75 and S100 gene expression induced by cell-imprinted substrate and beta-carotene to nerve tissue engineering

Dadashkhan S, Irani S, Bonakdar S, Ghalandari B (2021) P75 and S100 gene expression induced by cell-imprinted substrate and beta-carotene to nerve tissue engineering. Journal of Applied Polymer Science 138(26):50624. doi: 10.1002/app.50624 Objective: Aim to differentiate adipose-derived stem cells (ADSCs) to Schwann cells (SCs), as one of the major cell sources in nerve regeneration. Summary:

P75 and S100 gene expression induced by cell-imprinted substrate and beta-carotene to nerve tissue engineering Read More »

Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition

Wang Z, Jiang C, Yao H, Chen O, Rahman S, Gu Y, Zhao J, Huh Y, Ji RR (2021) Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition. Brain 144(2):665-681. doi: 10.1093/brain/awaa430 Summary: Itch is a common side effect of opioids, particularly as a result of epidural or intrathecal administration. Notably, morphine-elicited itch

Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition Read More »

The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis.

Zheng F, Chen J, Zhang X, Wang Z, Chen J, Lin X, Huang H, Fu W, Liang J, Wu W, Li B, Yao H, Hu H, Song E (2021) The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis. Nat Commun 12(1):1341. doi: 10.1038/s41467-021-21535-3 PMID: 33637716 Objective: To

The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis. Read More »

[Effect of salt intake on residual renal function in rats receiving peritoneal dialysis]

Kang H, Wang Y, Zhong X, Yin W, Li F, Jiang J (2021) [Effect of salt intake on residual renal function in rats receiving peritoneal dialysis]. Nan Fang Yi Ke Da Xue Xue Bao 41(2):264-271. doi: 10.12122/j.issn.1673-4254.2021.02.15 PMID: 33624601 Objective: To assess the effect of salt intake on residual renal function in rats and explore

[Effect of salt intake on residual renal function in rats receiving peritoneal dialysis] Read More »

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