Author name: Kristen Hartman

Lesions of the nucleus basalis magnocellularis induced by 192 IgG-saporin block memory enhancement with posttraining norepinephrine in the basolateral amygdala.

Power AE, Thal LJ, McGaugh JL (2002) Lesions of the nucleus basalis magnocellularis induced by 192 IgG-saporin block memory enhancement with posttraining norepinephrine in the basolateral amygdala. Proc Natl Acad Sci U S A 99(4):2315-2319. doi: 10.1073/pnas.022627799 Summary: There is evidence that memory consolidation (retention) can be modulated by drugs and stress hormones acting in […]

Lesions of the nucleus basalis magnocellularis induced by 192 IgG-saporin block memory enhancement with posttraining norepinephrine in the basolateral amygdala. Read More »

Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs.

Lembo PM, Grazzini E, Groblewski T, O’Donnell D, Roy MO, Zhang J, Hoffert C, Cao J, Schmidt R, Pelletier M, Labarre M, Gosselin M, Fortin Y, Banville D, Shen SH, Strom P, Payza K, Dray A, Walker P, Ahmad S (2002) Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs. Nat Neurosci

Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs. Read More »

Isoflurane and nociception: Spinal alpha2A adrenoceptors mediate antinociception while supraspinal alpha1 adrenoceptors mediate pronociception.

Kingery WS, Agashe GS, Guo TZ, Sawamura S, Davies MF, Clark JD, Kobilka BK, Maze M (2002) Isoflurane and nociception: Spinal alpha2A adrenoceptors mediate antinociception while supraspinal alpha1 adrenoceptors mediate pronociception. Anesthesiol 96:367-374. doi: 10.1097/00000542-200202000-00023 Summary: The authors injected 3 µg/3 µl of anti-DBH-SAP (Cat. #IT-03) into the lateral ventricle of rats to determine whether

Isoflurane and nociception: Spinal alpha2A adrenoceptors mediate antinociception while supraspinal alpha1 adrenoceptors mediate pronociception. Read More »

Targeting Tools: Serotonin Transporter Antibody

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Advanced Targeting Systems announces a new reagent for the study of the serotonergic systems—a monoclonal antibody to the serotonin transporter (Cat. #AB-N09). This murine monoclonal is made with a peptide from an extracellular domain of rat serotonin re-uptake transporter (SERT), and thus is able to attach to cells that express SERT. Homology with the human

Targeting Tools: Serotonin Transporter Antibody Read More »

Toxin Safety

Safety Instructions Good laboratory technique must be employed for the safe handling of this product. This requires observation of the following practices: 1. Wear appropriate laboratory attire, including lab coat, gloves and safety glasses. 2. Do not pipet by mouth, inhale, ingest or allow product to come into contact with open wounds. Wash thoroughly any

Toxin Safety Read More »

Cover Article: Control Conjugates – The Perfect Companion for Targeted Toxins

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Dr. Douglas Lappi, Chief Scientific Officer, Advanced Targeting Systems The field of targeted toxins has made enormous strides in the years since Advanced Targeting Systems introduced the first research targeted toxin in 1994. We now offer 16 different targeted toxins, with more on the way. The number of important papers in high impact journals continues

Cover Article: Control Conjugates – The Perfect Companion for Targeted Toxins Read More »

Cholinergic and noncholinergic septal neurons modulate strategy selection in spatial learning.

Cahill JFX, Baxter MG (2001) Cholinergic and noncholinergic septal neurons modulate strategy selection in spatial learning. Eur J Neurosci 14:1856-1864. doi: 10.1046/j.0953-816x.2001.01807.x Summary: The authors compared ibotenic acid (IA)-treated rats with those injected with 45 ng and 30 ng of 192-Saporin (Cat. #IT-01) into two separate coordinates of the medial septum/vertical limb of the diagonal

Cholinergic and noncholinergic septal neurons modulate strategy selection in spatial learning. Read More »

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