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Author name: Kristen Hartman

Revisiting the sigma-1 receptor as a biological target to treat affective and cognitive disorders

Sałaciak K, Pytka K (2022) Revisiting the sigma-1 receptor as a biological target to treat affective and cognitive disorders. Neurosci Biobehav Rev 132:1114-1136. doi: 10.1016/j.neubiorev.2021.10.037 Objective: This review focuses on the sigma-1 receptor as a target for treatment of depression and cognitive disorders. Summary: Sigma-1 receptor ligands, and predominantly agonists, might be the next generation […]

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Characterizing SERCA function in murine skeletal muscles after 35-37 days of spaceflight

Braun JL, Geromella MS, Hamstra SI, Messner HN, Fajardo VA (2021) Characterizing SERCA function in murine skeletal muscles after 35-37 days of spaceflight. Int J Mol Sci 22(21):11764. doi: 10.3390/ijms222111764 PMID: 34769190 Objective: To investigate SERCA function, SERCA regulatory protein content, and reactive oxygen/nitrogen species (RONS) protein adduction in murine skeletal muscle after 35–37 days

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Probing transferrin receptor overexpression in gastric cancer mice models

Lodhi MS, Khan MT, Bukhari SMH, Sabir SH, Samra ZQ, Butt H, Akram MS (2021) Probing transferrin receptor overexpression in gastric cancer mice models. ACS Omega 6(44):29893-29904. doi: 10.1021/acsomega.1c04382 PMID: 34778662 Objective: To investigate the role of the transferrin receptor, a glycoprotein receptor that is expressed many-folds on rapidly growing cells due to the greater

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Tart cherry extract and omega fatty acids reduce behavioral deficits, gliosis, and amyloid-beta deposition in the 5xFAD mouse model of Alzheimer’s disease

Bowers Z, Maiti P, Bourcier A, Morse J, Jenrow K, Rossignol J, Dunbar GL (2021) Tart cherry extract and omega fatty acids reduce behavioral deficits, gliosis, and amyloid-beta deposition in the 5xFAD mouse model of Alzheimer’s disease. Brain Sci 11(11):1423. doi: 10.3390/brainsci11111423 PMID: 34827424 Objective: To assess the efficacy of Total Body Rhythm (TBR) for

Tart cherry extract and omega fatty acids reduce behavioral deficits, gliosis, and amyloid-beta deposition in the 5xFAD mouse model of Alzheimer’s disease Read More »

Naturally occurring ribosome inactivating proteins might be key molecules against Covid-19

Arslan I, Aydin O, Birdal P (2021) Naturally occurring ribosome inactivating proteins might be key molecules against Covid-19. 2021 5th International Symposium on Multidisciplinary Studies and Innovative Technologies (ISMSIT) 624-627. Ankara, Turkey. doi: 10.1109/ISMSIT52890.2021.9604711 Summary: The authors cover a variety of topics related to the use of Saporin as a potential molecule to study for

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Role of microglia and astrocytes in spinal cord injury induced neuropathic pain

Miranpuri GS, Bali P, Nguyen J, Kim JJ, Modgil S, Mehra P, Buttar S, Brown G, Yutuc N, Singh H, Wood A, Singh J, Anand A (2021) Role of microglia and astrocytes in spinal cord injury induced neuropathic pain. Ann Neurosci 28(3-4):219-228. doi: 10.1177/09727531211046367 Summary: Given the severity and incapacitating effects of spinal cord injury

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Evaluation of the activity of choline acetyltransferase from different synaptosomal fractions at the distinct stages of spatial learning in the morris water maze

Storozheva ZI, Zakharova EI, Proshin AT (2021) Evaluation of the activity of choline acetyltransferase from different synaptosomal fractions at the distinct stages of spatial learning in the morris water maze. Front Behav Neurosci 15:755373. doi: 10.3389/fnbeh.2021.755373 Objective: To examine the role of hippocampal and cortical ACh in the acquisition, consolidation, storage, retention and adaptive flexibility

Evaluation of the activity of choline acetyltransferase from different synaptosomal fractions at the distinct stages of spatial learning in the morris water maze Read More »

Engrafted stem cell therapy for Alzheimer’s disease: A promising treatment strategy with clinical outcome

Salwa, LK (2021) Engrafted stem cell therapy for Alzheimer’s disease: A promising treatment strategy with clinical outcome. J Control Release 338:837-857. doi: 10.1016/j.jconrel.2021.09.007 Objective: This review provides a detailed update on stem cell therapy (SCT) for Alzheimer’s Disease (AD) Summary: What future holds for SCT in the treatment of AD is summarized Usage: Liu et

Engrafted stem cell therapy for Alzheimer’s disease: A promising treatment strategy with clinical outcome Read More »

Learning of food preferences: mechanisms and implications for obesity & metabolic diseases

Berthoud HR, Morrison CD, Ackroff K, Sclafani A (2021) Learning of food preferences: mechanisms and implications for obesity & metabolic diseases. Int J Obes (Lond) 45(10):2156-2168. doi: 10.1038/s41366-021-00894-3 Objective: This review focuses on postoral nutrient sensing and signaling as an essential part of the reward system that shapes preferences for the associated flavors of foods.

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