Author name: Kristen Hartman

Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis

Pehar M, Cassina P, Vargas MR, Castellanos R, Viera L, Beckman JS, Estévez AG, Barbeito L (2004) Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem 89(2):464-473. doi: 10.1111/j.1471-4159.2004.02357.x PMID: 15056289 Summary: The role of p75-mediated activity evaluated with p75NTR blocking antibody. Motor neuron loss induced by […]

Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis Read More »

Cover Article: 192 IgG-Saporin-Induced Lesions Identify an Inhibitory Role in Cocaine Reward for Cholinergic Neuronal Systems in the Diagonal Band and Ventral Pallidum

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Contributed by Dr. James Smith, Wake Forest University School of Medicine, Department of Physiology and Pharmacology, Medical Center Blvd, Winston-Salem NC 27157 Recent data implicate cholinergic neurons in the brain processes that underlie reinforcement. The involvement of cholinergic neurons in cocaine self-administration has been recently demonstrated using muscarinic and nicotinic agonists and antagonists, microdialysis, assessment

Cover Article: 192 IgG-Saporin-Induced Lesions Identify an Inhibitory Role in Cocaine Reward for Cholinergic Neuronal Systems in the Diagonal Band and Ventral Pallidum Read More »

Medullary serotonergic neurons and adjacent neurons that express neurokinin-1 receptors are both involved in chemoreception in vivo.

Nattie EE, Li A, Richerson GB, Lappi DA (2004) Medullary serotonergic neurons and adjacent neurons that express neurokinin-1 receptors are both involved in chemoreception in vivo. J Physiol 556(1):235-253. doi: 10.1113/jphysiol.2003.059766 PMID: 14724193 Summary: The retrotrapezoid nucleus contains neurokinin-1 receptor (NK-1r)-expressing neurons that are involved in chemoreception. NK-1r-expressing neurons are also present in areas that

Medullary serotonergic neurons and adjacent neurons that express neurokinin-1 receptors are both involved in chemoreception in vivo. Read More »

Habituation to stress and dexamethasone suppression in rats with selective basal forebrain cholinergic lesions.

Helm KA, Ziegler DR, Gallagher M (2004) Habituation to stress and dexamethasone suppression in rats with selective basal forebrain cholinergic lesions. Hippocampus 14(5):628-635. doi: 10.1002/hipo.10203 Summary: Basal forebrain cholinergic neurons may be involved in hippocampal and medial prefrontal cortex inhibition of glucocorticoid stress responses. The authors investigated the effects of 0.05 to 0.075 µg injections

Habituation to stress and dexamethasone suppression in rats with selective basal forebrain cholinergic lesions. Read More »

Evidence for nitric oxide involvement in experimental autoimmune encephalomyelitis and adjuvant-induced arthritis in Lewis rat.

Mnaimneh S, Damaj M, Barhoumi R, Mouneimne Y, Geffard M, Veyret B, Vincendeau P (2004) Evidence for nitric oxide involvement in experimental autoimmune encephalomyelitis and adjuvant-induced arthritis in Lewis rat. The Pain Clinic 16(3):229-243. doi: 10.1163/1568569041798407 PMID: 0 Related Products: NO-L-Cysteine Mouse Monoclonal, Conjugated (Cat. #AB-T125)

Evidence for nitric oxide involvement in experimental autoimmune encephalomyelitis and adjuvant-induced arthritis in Lewis rat. Read More »

Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines.

Zhang Y, Berger SA (2004) Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines. J Biol Chem 279(8):6507-6516. doi: 10.1074/jbc.M306117200 Summary: Ca2+ plays a vital role in many cell processes. To investigate events associated with Ca2+ and endoplasmic reticulum (ER) stress-induced cell death, the

Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines. Read More »

Environment-spatial conditional learning in rats with selective lesions of medial septal cholinergic neurons.

Janisiewicz AM, Jackson O, Firoz EF, Baxter MG (2004) Environment-spatial conditional learning in rats with selective lesions of medial septal cholinergic neurons. Hippocampus 14:265-273. doi: 10.1002/hipo.10175 Summary: 192-Saporin (Cat. #IT-01) has produced varied results when used to determine the role of cholinergic neurons of the medial septum/vertical limb of the diagonal band (MS/VDB) in spatial

Environment-spatial conditional learning in rats with selective lesions of medial septal cholinergic neurons. Read More »

Effects of complete immunotoxin lesions of the cholinergic basal forebrain on fear conditioning and spatial learning.

Frick KM, Jeansok JK, Baxter MG (2004) Effects of complete immunotoxin lesions of the cholinergic basal forebrain on fear conditioning and spatial learning. Hippocampus 14:244-254. doi: 10.1002/hipo.10169 Summary: The authors examined the hypothesis that basal forebrain cholinergic neurons are critical for acquisition and consolidation of fear conditioning by lesioning the medial septum/vertical limb of the

Effects of complete immunotoxin lesions of the cholinergic basal forebrain on fear conditioning and spatial learning. Read More »

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