Author name: Kristen Hartman

Bovine bone gelatin-derived peptides: Food processing characteristics and evaluation of antihypertensive and antihyperlipidemic activities

Cao S, Wang Z, Xing L, Zhou L, Zhang W (2022) Bovine bone gelatin-derived peptides: Food processing characteristics and evaluation of antihypertensive and antihyperlipidemic activities. J Agric Food Chem 70(32):9877-9887. doi: 10.1021/acs.jafc.2c02982 PMID: 35917452 Objective: To evaluate the food processing properties of bovine bone gelatin-derived peptides (BGPs) and their effects and mechanisms on hypertension and […]

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In vivo visualization and molecular targeting of the cardiac conduction system

Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM (2022) In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest e156955. doi: 10.1172/jci156955 Objective: To engineer

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Cannabinoid receptors and glial response following a basal forebrain cholinergic lesion

Llorente-Ovejero A, Bengoetxea de Tena I, Martínez-Gardeazabal J, Moreno-Rodríguez M, Lombardero L, Manuel I, Rodríguez-Puertas R (2022) Cannabinoid receptors and glial response following a basal forebrain cholinergic lesion. ACS Pharmacol Transl Sci 5(9):791-802. doi: 10.1021/acsptsci.2c00069 PMID: 36110372 Objective: The endocannabinoid system is involved in the control of learning, memory, and neuroinflammatory processes and plays a

Cannabinoid receptors and glial response following a basal forebrain cholinergic lesion Read More »

Self-assembling nanocarriers from engineered proteins: Design, functionalization, and application for drug delivery

Li Y, Champion JA (2022) Self-assembling nanocarriers from engineered proteins: Design, functionalization, and application for drug delivery. Adv Drug Deliv Rev 189:114462. doi: 10.1016/j.addr.2022.114462 PMID: 35934126 Objective: Review recent advances in protein nano-carriers that are from ground-up design recombinant proteins. Summary: Nanocarriers with a size range of 10-200 nm have emerged as platforms with significant

Self-assembling nanocarriers from engineered proteins: Design, functionalization, and application for drug delivery Read More »

Long-term nucleus basalis cholinergic depletion induces attentional deficits and impacts cortical neurons and BDNF levels without affecting the NGF synthesis

Orciani C, Hall H, Pentz R, Foret MK, Do Carmo S, Cuello AC (2022) Long-term nucleus basalis cholinergic depletion induces attentional deficits and impacts cortical neurons and BDNF levels without affecting the NGF synthesis. J Neurochem 163(2):149-167. doi: 10.1111/jnc.15683 PMID: 35921478 Objective: To determine whether reciprocal interaction of basal forebrain cholinergic neurons (BFCN) impact neurotrophin

Long-term nucleus basalis cholinergic depletion induces attentional deficits and impacts cortical neurons and BDNF levels without affecting the NGF synthesis Read More »

Stimulation of Akt phosphorylation and glucose transport by metalloporphyrins with peroxynitrite decomposition catalytic activity

Eccardt AM, Pelzel RJ, Bell TP, Fisher JS (2022) Stimulation of Akt phosphorylation and glucose transport by metalloporphyrins with peroxynitrite decomposition catalytic activity. Catalysts 12(8):849. doi: 10.3390/catal12080849 PMID: 37123089 Objective: To determine whether a catalytic action of iron porphyrin compounds would be related to their stimulation of insulin signaling and glucose uptake in C2C12 myotubes.

Stimulation of Akt phosphorylation and glucose transport by metalloporphyrins with peroxynitrite decomposition catalytic activity Read More »

Perinatal correlated retinal activity is required for the wiring of visual axons in non-image forming nuclei

Negueruela S, Morenilla C, Herrera M, Coca Y, Florez-Paz D, López-Cascales MT, Gomis A, Herrera E (2022) Perinatal correlated retinal activity is required for the wiring of visual axons in non-image forming nuclei. bioRxiv 2022.07.27.501692. doi: 10.1101/2022.07.27.501692 Related Products: Melanopsin Rabbit Polyclonal (Cat. #AB-N38)

Perinatal correlated retinal activity is required for the wiring of visual axons in non-image forming nuclei Read More »

Differential role of GABAergic and cholinergic ventral pallidal neurons in behavioral despair, conditioned fear memory and active coping.

Akmese C, Sevinc C, Halim S, Unal G (2022) Differential role of GABAergic and cholinergic ventral pallidal neurons in behavioral despair, conditioned fear memory and active coping. bioRxiv 2022.07.21.500949. doi: 10.1101/2022.07.21.500949 Related Products: 192-IgG-SAP (Cat. #IT-01), GAT1-SAP (Cat. #IT-32)

Differential role of GABAergic and cholinergic ventral pallidal neurons in behavioral despair, conditioned fear memory and active coping. Read More »

Saporin toxin delivered by engineered colloidal nanoparticles is strongly effective against cancer cells

Salvioni L, Testa F, Barbieri L, Giustra M, Bertolini JA, Tomaino G, Tortora P, Prosperi D, Colombo M (2022) Saporin toxin delivered by engineered colloidal nanoparticles is strongly effective against cancer cells. Pharmaceutics 14(7):1517. doi: 10.3390/pharmaceutics14071517 PMID: 35890411 Objective: Using Saporin-containing iron oxide nanoparticles to selectively eliminate cancer cells. Summary: Saporin [PR-01] is trapped inside

Saporin toxin delivered by engineered colloidal nanoparticles is strongly effective against cancer cells Read More »

A century searching for the neurons necessary for wakefulness

Grady FS, Boes AD, Geerling JC (2022) A century searching for the neurons necessary for wakefulness. Front Neurosci 16:930514. doi: 10.3389/fnins.2022.930514 Objective: This review article attempts to summarize research that has investigated the neurons necessary for wakefulness. Summary: The authors summarize animal experiments and research performed in different brain regions to further understand wakefulness. Several

A century searching for the neurons necessary for wakefulness Read More »

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