Author name: Kristen Hartman

Septohippocampal GABAergic neurons mediate the altered behaviors induced by n-methyl-D-aspartate receptor antagonists.

Ma J, Tai SK, Leung LS (2012) Septohippocampal GABAergic neurons mediate the altered behaviors induced by n-methyl-D-aspartate receptor antagonists. Hippocampus 22(12):2208-2218. doi: 10.1002/hipo.22039 Summary: It is thought that the integrity of the medial septum is essential for the maintenance of hippocampal theta rhythm – and that this maintenance depends on three types of septohippocampal neurons; […]

Septohippocampal GABAergic neurons mediate the altered behaviors induced by n-methyl-D-aspartate receptor antagonists. Read More »

Local serotonin mediates cyclic strain-induced phenotype transformation, matrix degradation, and glycosaminoglycan synthesis in cultured sheep mitral valves.

Lacerda CM, Kisiday J, Johnson B, Orton EC (2012) Local serotonin mediates cyclic strain-induced phenotype transformation, matrix degradation, and glycosaminoglycan synthesis in cultured sheep mitral valves. Am J Physiol Heart Circ Physiol 302(10):H1983-90. doi: 10.1152/ajpheart.00987.2011 PMID: 22345569 Summary: Calcific aortic valve disease and myxomatous mitral valve disease (MMVD) are the most commonly seen degenerative heart

Local serotonin mediates cyclic strain-induced phenotype transformation, matrix degradation, and glycosaminoglycan synthesis in cultured sheep mitral valves. Read More »

Prior pathology in the basal forebrain cholinergic system predisposes to inflammation-induced working memory deficits: Reconciling inflammatory and cholinergic hypotheses of delirium.

Field RH, Gossen A, Cunningham C (2012) Prior pathology in the basal forebrain cholinergic system predisposes to inflammation-induced working memory deficits: Reconciling inflammatory and cholinergic hypotheses of delirium. J Neurosci 32(18):6288-6294. doi: 10.1523/JNEUROSCI.4673-11.2012 Summary: The authors lesioned the basal forebrain of mice with 0.08 μg or 0.4 μg icv injections of mu p75-SAP (Cat. #IT-16)

Prior pathology in the basal forebrain cholinergic system predisposes to inflammation-induced working memory deficits: Reconciling inflammatory and cholinergic hypotheses of delirium. Read More »

Involvement of brain-derived neurotrophic factor and sonic hedgehog in the spinal cord plasticity after neurotoxic partial removal of lumbar motoneurons.

Gulino R, Gulisano M (2012) Involvement of brain-derived neurotrophic factor and sonic hedgehog in the spinal cord plasticity after neurotoxic partial removal of lumbar motoneurons. Neurosci Res 73(3):238-247. doi: 10.1016/j.neures.2012.04.010 Summary: In this work the authors created a motoneuron depletion with bilateral 6.0-μg injections of CTB-SAP (Cat. #IT-14) into the medial and lateral gastrocnemius muscles

Involvement of brain-derived neurotrophic factor and sonic hedgehog in the spinal cord plasticity after neurotoxic partial removal of lumbar motoneurons. Read More »

Intraneural OX7-saporin for neuroma-in-continuity in a rat model.

Mavrogenis AF, Pavlakis K, Stamatoukou A, Papagelopoulos PJ, Theoharis S, Zetahang Z, Soucacos PN, Zoubos AB (2013) Intraneural OX7-saporin for neuroma-in-continuity in a rat model. Eur J Orthop Surg Traumatol 23(3):263-272. doi: 10.1007/s00590-012-0996-x Summary: The authors created a model of neuroma-in-continuity to explore the effect of OX7-SAP (Cat. #IT-02) on the neuroma. The left common

Intraneural OX7-saporin for neuroma-in-continuity in a rat model. Read More »

Lamina I NK1 expressing projection neurones are functional in early postnatal rats and contribute to the setting up of adult mechanical sensory thresholds.

Man SH, Geranton SM, Hunt SP (2012) Lamina I NK1 expressing projection neurones are functional in early postnatal rats and contribute to the setting up of adult mechanical sensory thresholds. Mol Pain 8(1):35. doi: 10.1186/1744-8069-8-35 Summary: Projections from lamina I neurons regulate mechanical and thermal sensitivity due to injury. Little is known about how these

Lamina I NK1 expressing projection neurones are functional in early postnatal rats and contribute to the setting up of adult mechanical sensory thresholds. Read More »

Consequences of the ablation of nonpeptidergic afferents in an animal model of trigeminal neuropathic pain.

Taylor AM, Osikowicz M, Ribeiro-da-Silva A (2012) Consequences of the ablation of nonpeptidergic afferents in an animal model of trigeminal neuropathic pain. Pain 153(6):1311-1319. doi: 10.1016/j.pain.2012.03.023 Summary: The authors used IB4-SAP (Cat. #IT-10; 3.2 μg injected into the mental nerve) to eliminate C-fibers in the lower lip of rats to see if this was enough

Consequences of the ablation of nonpeptidergic afferents in an animal model of trigeminal neuropathic pain. Read More »

c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections.

Hu J, Huang T, Li T, Guo Z, Cheng L (2012) c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections. J Neurosci 32(16):5362-5373. doi: 10.1523/JNEUROSCI.6239-11.2012 PMID: 22514301 Summary: The molecular mechanisms responsible for development of laminae III/IV neurons are not yet well understood. In this work the

c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections. Read More »

Arcuate kisspeptin/neurokinin b/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight.

Mittelman-Smith MA, Williams H, Krajewski-Hall SJ, Lai J, Ciofi P, McMullen NT, Rance NE ( 2012 ) Arcuate kisspeptin/neurokinin b/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight. Endocrinology 153(6):2800-2812 . doi: 10.1210/en.2012-1045 Related Products: NKB-SAP (Cat. #IT-63), Blank-SAP (Cat. #IT-21) Read the featured article in Targeting Trends.

Arcuate kisspeptin/neurokinin b/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight. Read More »

Intrinsic voltage dynamics govern the diversity of spontaneous firing profiles in basal forebrain noncholinergic neurons.

Ovsepian SV, Dolly JO, Zaborszky L (2012) Intrinsic voltage dynamics govern the diversity of spontaneous firing profiles in basal forebrain noncholinergic neurons. J Neurophysiol 108(2):406-418. doi: 10.1152/jn.00642.2011 PMID: 22496531 Summary: The voltage modulation functions of the basal forebrain have commonly been associated with cholinergic cells. More recent work has suggested that noncholinergic cells have an

Intrinsic voltage dynamics govern the diversity of spontaneous firing profiles in basal forebrain noncholinergic neurons. Read More »

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