Author name: Kristen Hartman

Combinatorial treatment of tart cherry extract and essential fatty acids reduces cognitive impairments and inflammation in the mu-p75 saporin-induced mouse model of Alzheimer’s disease.

Matchynski JJ, Lowrance SA, Pappas C, Rossignol J, Puckett N, Sandstrom M, Dunbar GL (2013) Combinatorial treatment of tart cherry extract and essential fatty acids reduces cognitive impairments and inflammation in the mu-p75 saporin-induced mouse model of Alzheimer’s disease. J Med Food 16(4):288-295. doi: 10.1089/jmf.2012.0131 PMID: 23566055 Summary: The authors investigated the efficacy of a […]

Combinatorial treatment of tart cherry extract and essential fatty acids reduces cognitive impairments and inflammation in the mu-p75 saporin-induced mouse model of Alzheimer’s disease. Read More »

The role of visual cortex acetylcholine in learning to discriminate temporally modulated visual stimuli.

Minces VH, Alexander AS, Datlow M, Alfonso SI, Chiba AA (2013) The role of visual cortex acetylcholine in learning to discriminate temporally modulated visual stimuli. Front Behav Neurosci 7:16. doi: 10.3389/fnbeh.2013.00016 Summary: In order to examine some of the minor differences in the temporal structure of stimuli, the authors bilaterally injected 37.5 ng of 192-IgG-SAP

The role of visual cortex acetylcholine in learning to discriminate temporally modulated visual stimuli. Read More »

Immunohistochemical localization of AT1a, AT1b, and AT2 Angiotensin II receptor subtypes in the rat adrenal, pituitary, and brain with a perspective commentary.

Premer C, Lamondin C, Mitzey A, Speth R, Brownfield M (2013) Immunohistochemical localization of AT1a, AT1b, and AT2 Angiotensin II receptor subtypes in the rat adrenal, pituitary, and brain with a perspective commentary. Int J Hypertens 2013:175428. doi: 10.1155/2013/175428 PMID: 23573410 Objective: To immunohistochemically differentiate the angiotensin receptor subtypes: AT-1ARa, AT-1ARb, and AT-2R. Summary: Antibodies

Immunohistochemical localization of AT1a, AT1b, and AT2 Angiotensin II receptor subtypes in the rat adrenal, pituitary, and brain with a perspective commentary. Read More »

Methods for evaluating cell-specific, cell-internalizing RNA aptamers.

Hernandez L, Flenker K, Hernandez F, Klingelhutz A, McNamara J, Giangrande P (2013) Methods for evaluating cell-specific, cell-internalizing RNA aptamers. Pharmaceuticals (Basel) 6:295-319. doi: 10.3390/ph6030295 Objective: Isolate aptamers that internalize upon binding to their cognate receptor on the cell surface Summary: Among the methods used to characterize aptamers that internalize is a way to monitor

Methods for evaluating cell-specific, cell-internalizing RNA aptamers. Read More »

Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice.

Laursen B, Mork A, Plath N, Kristiansen U, Bastlund JF (2013) Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice. Behav Brain Res 240:146-152. doi: 10.1016/j.bbr.2012.11.012 Summary: Extracellular plaques containing amyloid β-peptides (Aβ) and cholinergic dysfunction are two of the main hallmarks of Alzheimer’s disease. Using a transgenic mouse line

Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice. Read More »

Targeted toxin-based selectable drug-free enrichment of Mammalian cells with high transgene expression.

Sato M, Akasaka E, Saitoh I, Ohtsuka M, Nakamura S, Sakurai T, Watanabe S (2013) Targeted toxin-based selectable drug-free enrichment of Mammalian cells with high transgene expression. Biology (Basel) 2:341-355. doi: 10.3390/biology2010341 Summary: Cell transfection is a powerful tool for evaluation of function and expression of newly discovered genes as well as for both small

Targeted toxin-based selectable drug-free enrichment of Mammalian cells with high transgene expression. Read More »

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.

Koch H, Zanella S, Elsen GE, Smith L, Doi A, Garcia AJr, Wei AD, Xun R, Kirsch S, Gomez CM, Hevner RF, Ramirez JM (2013) Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels. J Neurosci 33(8):3633-3645. doi: 10.1523/JNEUROSCI.6390-11.2013 PMID: 23426690 Summary: Pharmacological experiments have suggested that sighs and normal respiration are highly

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels. Read More »

Cognitive performance as a zeitgeber: cognitive oscillators and cholinergic modulation of the SCN entrain circadian rhythms

Gritton HJ, Stasiak AM, Sarter M, Lee TM (2013) Cognitive performance as a zeitgeber: cognitive oscillators and cholinergic modulation of the SCN entrain circadian rhythms. PLoS One 8(2):e56206. doi: 10.1371/journal.pone.0056206 PMID: 23441168 Objective: To examine how attention-demanding task performance interacts with circadian mechanisms in the SCN. Summary: The authors used site-specific injections of the 192

Cognitive performance as a zeitgeber: cognitive oscillators and cholinergic modulation of the SCN entrain circadian rhythms Read More »

Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’ breast cancer cell type.

Rust S, Guillard S, Sachsenmeier K, Hay C, Davidson M, Karlsson A, Karlsson R, Brand E, Lowne D, Elvin J, Flynn M, Kurosawa G, Hollingsworth R, Jermutus L, Minter R (2013) Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’ breast cancer cell type. Mol Cancer 12:11. doi: 10.1186/1476-4598-12-11 Summary: The

Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’ breast cancer cell type. Read More »

Plasmin induces intercellular adhesion molecule 1 expression in human endothelial cells via nuclear factor-κB/mitogen-activated protein kinases-dependent pathways.

Li Q, Syrovets T, Simmet T, Ding J, Xu J, Chen W, Zhu D, Gao P (2013) Plasmin induces intercellular adhesion molecule 1 expression in human endothelial cells via nuclear factor-κB/mitogen-activated protein kinases-dependent pathways. Exp Biol Med (Maywood) 238(2):176-186. doi: 10.1177/1535370212473700 Summary: Intracellular adhesion molecule 1 (ICAM-1) mediates inflammatory cell migration – an early step

Plasmin induces intercellular adhesion molecule 1 expression in human endothelial cells via nuclear factor-κB/mitogen-activated protein kinases-dependent pathways. Read More »

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