Author name: Kristen Hartman

Cover Article: Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits in an NGFr-lesioned mouse model

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Contributed by Liu Y, Weick JP, Liu H, Krencik R, Zhang X, Ma L, Zhou GM, Ayala M, Zhang SC. Waisman Center, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA. and Human Anatomy and Histology, Fudan University Shanghai Medical School, Shanghai, China. Basal forebrain neurons including cholinergic neurons and GABA interneurons […]

Cover Article: Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits in an NGFr-lesioned mouse model Read More »

Angiotensin II’s role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic

Johnson PL, Sajdyk TJ, Fitz SD, Hale MW, Lowry CA, Hay-Schmidt A, Shekhar A (2013) Angiotensin II’s role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic. Prog Neuropsychopharmacol Biol Psychiatry 44:248-256. doi: 10.1016/j.pnpbp.2013.02.014 PMID: 23523745 Objective: To test the hypothesis that the

Angiotensin II’s role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic Read More »

A robust method to derive functional neural crest cells from human pluripotent stem cells

Kreitzer FR, Salomonis N, Sheehan A, Huang M, Park JS, Spindler MJ, Lizarraga P, Weiss WA, So PL, Conklin BR (2013) A robust method to derive functional neural crest cells from human pluripotent stem cells. Am J Stem Cells 2(2):119-131. PMID: 23862100 Usage: Immunocytochemistry 1:200 Related Products: NGFr (ME20.4, p75) Mouse Monoclonal (Cat. #AB-N07)

A robust method to derive functional neural crest cells from human pluripotent stem cells Read More »

Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties.

Bostad M, Berg K, Hogset A, Skarpen E, Stenmark H, Selbo PK (2013) Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties. J Control Release 168(3):317-326. doi: 10.1016/j.jconrel.2013.03.023 Summary: Targeted therapies for cancer can be trapped in the lysosome and compartmentalized away

Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties. Read More »

Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells

Ben-David U, Nudel N, Benvenisty N (2013) Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells. Nat Commun 4:1992. doi: 10.1038/ncomms2992 PMID: 23778593 Objective: To identify a pluripotent cell specific surface marker and develop strategies to selectively eliminate tumorigenic human pluripotent stem cells (hPSCs) from mixed cell populations. Summary:

Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells Read More »

A novel model for evaluating therapies targeting human tumor vasculature and human cancer stem-like cells.

Burgos-Ojeda D, McLean K, Bai S, Pulaski H, Gong Y, Silva I, Skorecki K, Tzukerman M, Buckanovich RJ (2013) A novel model for evaluating therapies targeting human tumor vasculature and human cancer stem-like cells. Cancer Res 73(12):3555-3565. doi: 10.1158/0008-5472.CAN-12-2845 Objective: To evaluate tumor vascular markers (TVM) expression in a human embryonic stem cell–derived teratoma (hESCT)

A novel model for evaluating therapies targeting human tumor vasculature and human cancer stem-like cells. Read More »

Time course study of targeted ablation of KNDy neurons, but not tyrosine-hydroxylase neurons, in the rat arcuate nucleus using a neurokinin b-saporin.

Helena CV, Kalil B, Anselmo-Franci JA, Bertram R (2013) Time course study of targeted ablation of KNDy neurons, but not tyrosine-hydroxylase neurons, in the rat arcuate nucleus using a neurokinin b-saporin. Endocr Rev 34:OR47-5. 95th Annual Meetin and Expo, San Francisco. doi: 10.1093/edrv/34.supp.1 Summary: Ovariectomized rats were given bilateral injections of NK3-SAP (Cat. #IT-63) into

Time course study of targeted ablation of KNDy neurons, but not tyrosine-hydroxylase neurons, in the rat arcuate nucleus using a neurokinin b-saporin. Read More »

P2Y1 receptors expressed by C1 neurons determine peripheral chemoreceptor modulation of breathing, sympathetic activity, and blood pressure.

Wenker IC, Sobrinho CR, Takakura AC, Mulkey DK, Moreira TS (2013) P2Y1 receptors expressed by C1 neurons determine peripheral chemoreceptor modulation of breathing, sympathetic activity, and blood pressure. Hypertension 62(2):263-273. doi: 10.1161/HYPERTENSIONAHA.113.01487 Summary: Peripheral chemoreceptor activation response is mediated by catecholaminergic C1 cells in the rostral ventrolateral medulla (RVLM). The authors investigated the molecular mechanisms

P2Y1 receptors expressed by C1 neurons determine peripheral chemoreceptor modulation of breathing, sympathetic activity, and blood pressure. Read More »

A small molecule angiotensin II type 2 receptor (AT₂R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia

Smith MT, Woodruff TM, Wyse BD, Muralidharan A, Walther T (2013) A small molecule angiotensin II type 2 receptor (AT₂R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia. Pain Med 14(10):1557-1568. doi: 10.1111/pme.12157 PMID: 23742186 Objective:

A small molecule angiotensin II type 2 receptor (AT₂R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia Read More »

An environment-dependent modulation of cortical neural response by forebrain cholinergic neurons in awake rat.

Ariffin MZ, Chang LS, Koh HC, Low CM, Khanna S (2013) An environment-dependent modulation of cortical neural response by forebrain cholinergic neurons in awake rat. Brain Res 1513:72-84. doi: 10.1016/j.brainres.2013.03.046 Summary: Rats received 168 ng of 192-IgG-SAP (Cat. #IT-01) into the medial septum and induction of c-Fos expression in response to either familiar or novel

An environment-dependent modulation of cortical neural response by forebrain cholinergic neurons in awake rat. Read More »

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