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  4. Angiotensin II’s role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic

Angiotensin II’s role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic

Johnson PL, Sajdyk TJ, Fitz SD, Hale MW, Lowry CA, Hay-Schmidt A, Shekhar A (2013) Angiotensin II’s role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic. Prog Neuropsychopharmacol Biol Psychiatry 44:248-256. doi: 10.1016/j.pnpbp.2013.02.014 PMID: 23523745

Objective: To test the hypothesis that the subfornical organ (SFO) projects to the basolateral amygdala (BLA) and releases angiotensin-II (A-11) to mobilize panic responses.

Summary: The presence of AT-1R was confirmed in the BLA which, combined with previous data, suggests that A-II’s panicogenic effects in the BLA are AT-1R dependent.

Usage: Immunohistochemistry (1:250 to 1:500).

Related Products: Angiotensin II receptor (AT-1R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N27AP)

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