Author name: Kristen Hartman

Descending noradrenergic control of conditioned pain modulation and postoperative pain trajectory in rats.

Parker RA, Wang F, Hayashida K, Martin TJ, Eisenach JC, Peters CM (2013) Descending noradrenergic control of conditioned pain modulation and postoperative pain trajectory in rats. Neuroscience 2013 Abstracts 461.10. Society for Neuroscience, San Diego, CA. Summary: Aim of Investigation: Chronic pain after surgery (CPAS) is now recognized as a significant clinical problem that occurs […]

Descending noradrenergic control of conditioned pain modulation and postoperative pain trajectory in rats. Read More »

Neuroprotection with gonadal steroids following partial motoneuron depletion: Dependence on steroid receptor activation and hormone action at the target musculature.

Sengelaub DR, Cai Y, Chung M, Mnayarji (2013) Neuroprotection with gonadal steroids following partial motoneuron depletion: Dependence on steroid receptor activation and hormone action at the target musculature. Neuroscience 2013 Abstracts 467.12. Society for Neuroscience, San Diego, CA. Summary: Aim of Investigation: Chronic pain after surgery (CPAS) is now recognized as a significant clinical problem

Neuroprotection with gonadal steroids following partial motoneuron depletion: Dependence on steroid receptor activation and hormone action at the target musculature. Read More »

Role of nonpeptidergic subset of primary afferent neurons in inflammatory hypernociception in mice.

Pinto LG, Souza GR, Lopes AHP, Talbot J, Cunha FQ, Cunha TM, Ferreira SH (2013) Role of nonpeptidergic subset of primary afferent neurons in inflammatory hypernociception in mice. Neuroscience 2013 Abstracts 256.15. Society for Neuroscience, San Diego, CA. Summary: Sensory information is transmitted from the periphery to the spinal cord by distinct subsets of primary

Role of nonpeptidergic subset of primary afferent neurons in inflammatory hypernociception in mice. Read More »

Ablation of arcuate KNDy neurons amplifies the LH surge in steroid-primed, ovariectomized rats.

Krajewski-Hall SJ, Mittelman-Smith, Mcmullen NT, Rance NE (2013) Ablation of arcuate KNDy neurons amplifies the LH surge in steroid-primed, ovariectomized rats. Neuroscience 2013 Abstracts 274.01. Society for Neuroscience, San Diego, CA. Summary: KNDy (kisspeptin, neurokinin B and dynorphin) neurons in the arcuate nucleus play an important role in the reproductive axis. We have developed a

Ablation of arcuate KNDy neurons amplifies the LH surge in steroid-primed, ovariectomized rats. Read More »

Loss of medial prefrontal cortical cholinergic projections increases preference for an immediately available reward in a delay discounting task.

Burk JA, Yonezaki K (2013) Loss of medial prefrontal cortical cholinergic projections increases preference for an immediately available reward in a delay discounting task. Neuroscience 2013 Abstracts 288.02. Society for Neuroscience, San Diego, CA. Summary: Attentional control is thought to regulate numerous processes, including impulsive choices. The cholinergic projections to the medial prefrontal cortex are

Loss of medial prefrontal cortical cholinergic projections increases preference for an immediately available reward in a delay discounting task. Read More »

Selective basal forebrain cholinergic deficits reduce glucose metabolism, cholinergic and GABAergic system in the cingulate cortex.

Lee J, Jeong D, Oh J, Lee J, Chang W, Cho Z, Chang J (2013) Selective basal forebrain cholinergic deficits reduce glucose metabolism, cholinergic and GABAergic system in the cingulate cortex. Neuroscience 2013 Abstracts 45.12. Society for Neuroscience, San Diego, CA. Summary: Reduction of brain glucose metabolism and degeneration of cholinergic basal forebrain neurons are

Selective basal forebrain cholinergic deficits reduce glucose metabolism, cholinergic and GABAergic system in the cingulate cortex. Read More »

Intrathecal substance p-saporin in the dog: distribution, safety, and spinal neurokinin-1 receptor ablation.

Wiese AJ, Rathbun M, Butt MT, Malkmus SA, Richter PJ, Osborn KG, Xu Q, Veesart SL, Steinauer JJ, Higgins D, Lappi DA, Russell B, Yaksh TL (2013) Intrathecal substance p-saporin in the dog: distribution, safety, and spinal neurokinin-1 receptor ablation. Anesthesiology 119(5):1163-1177. doi: 10.1097/ALN.0b013e3182a95164 Summary: Here the authors investigate the safety parameters of SP-SAP on

Intrathecal substance p-saporin in the dog: distribution, safety, and spinal neurokinin-1 receptor ablation. Read More »

Intrathecal substance p-saporin in the dog: efficacy in bone cancer pain.

Brown DC, Agnello K (2013) Intrathecal substance p-saporin in the dog: efficacy in bone cancer pain. Anesthesiology 119(5):1178-1185. doi: 10.1097/ALN.0b013e3182a95188 Summary: This work demonstrates the use of naturally occurring bone cancer in dogs as a model for pain therapy. Companion dogs with bone cancer received 20-60 μg intrathecal injections of SP-SAP (currently in human clinical

Intrathecal substance p-saporin in the dog: efficacy in bone cancer pain. Read More »

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