Read the 2009 Newsletters and recent scientific references 2009, issue 1: Selective deletion of CD8+ T cells by saporin-coupled MHC class I tetramers / by Hess PR, Buntzman AS, Murray SL, Young EF, Frelinger JA / featuring Streptavidin-ZAP (Cat. #IT-27), FITC-labeled SAP antibody (Cat. #FL-02) SFN Poster of the Year Targeting Talk: IgM Primary Antibody Assay 2009, issue 2: […]
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CTB-SAP (Cat. #IT-14) is a conjugate between the cell-binding component of cholera toxin (the B chain) and saporin. CTB binds to GM1 (monosialotetrahexosylganglioside), which is present on the surface of different neurons. It has been suggested to be involved in many problems (besides the most famous in the gut: cholera) of neuronal systems: Parkinson’s, motor
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This secondary conjugate (molecular weight 210 kDa) recognizes YOUR human monoclonal IgM antibody. Hug-M-ZAP (IT-43) is a chemical conjugate of affinity-purified goat anti-human IgM and the ribosome-inactivating protein, saporin. Hug-M- ZAP uses your primary human monoclonal IgM antibody to target and eliminate cells and can be used to evaluate the potential of a primary antibody
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Contributed by Arshad M. Khan, Kimberly L. Rapp, Todd A. Ponzio, Graciela Sanchez-Watts and Alan G. Watts; Dept. of Biological Sciences and Neuroscience Research Institute, University of Southern California, Los Angeles, CA; and Laboratory for Neurochemistry, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD The brain has evolved adaptive mechanisms for